Temozolomide-Induced Shrinkage of Invasive Pituitary Adenoma in Patient with Nelson’s Syndrome: A Case Report and Review of the Literature
المؤلفون المشاركون
Kurowska, Maria
Nowakowski, Andrzej
Zieliński, Grzegorz
Malicka, Joanna
Tarach, Jerzy S.
Maksymowicz, Maria
Denew, Piotr
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-06-29
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Introduction.
Invasive tumours in Nelson’s syndrome need aggressive therapy.
Recent reports have documented the efficacy of temozolomide (TMZ) in the treatment of adenomas resistant to conventional management.
Objective.
The review of the literature concerning TMZ treatment of atypical corticotroph adenomas and a case study of 56-year-old woman who developed Nelson’s syndrome.
Treatment Proceeding.
The patient with Cushing’s disease underwent transsphenoidal adenomectomy followed by a 27-month-long period of remission.
Due to a regrowth of the tumor, she underwent two reoperations followed by stereotactic radiotherapy.
Because of treatment failures, bilateral adrenalectomy was performed.
Then she developed Nelson’s syndrome.
A fourth transsphenoidal adenomectomy was performed, but there was a rapid recurrence.
Five months later, she underwent a right frontotemporal craniotomy.
Due to a rapid regrowth of the tumour, the patient did not receive gamma-knife therapy and was treated with cabergoline and somatostatin analogue for some time.
Only TMZ therapy resulted in marked clinical, biochemical, and radiological improvement.
To date, this is the first case of invasive corticotroph adenoma in Nelson’s syndrome treated with temozolomide in Poland.
Conclusion.
In our opinion, temozolomide can be an effective treatment option of invasive adenomas in Nelson’s syndrome.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kurowska, Maria& Nowakowski, Andrzej& Zieliński, Grzegorz& Malicka, Joanna& Tarach, Jerzy S.& Maksymowicz, Maria…[et al.]. 2015. Temozolomide-Induced Shrinkage of Invasive Pituitary Adenoma in Patient with Nelson’s Syndrome: A Case Report and Review of the Literature. Case Reports in Endocrinology،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1058409
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kurowska, Maria…[et al.]. Temozolomide-Induced Shrinkage of Invasive Pituitary Adenoma in Patient with Nelson’s Syndrome: A Case Report and Review of the Literature. Case Reports in Endocrinology No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1058409
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kurowska, Maria& Nowakowski, Andrzej& Zieliński, Grzegorz& Malicka, Joanna& Tarach, Jerzy S.& Maksymowicz, Maria…[et al.]. Temozolomide-Induced Shrinkage of Invasive Pituitary Adenoma in Patient with Nelson’s Syndrome: A Case Report and Review of the Literature. Case Reports in Endocrinology. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1058409
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1058409
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر