Fatal Epstein-Barr Virus Reactivation in an Acquired Aplastic Anemia Patient Treated with Rabbit Antithymocyte Globulin and Cyclosporine A
المؤلفون المشاركون
Takahashi, Tohru
Maruyama, Yumiko
Saitoh, Mayuko
Itoh, Hideto
Yoshimoto, Mitsuru
Tsujisaki, Masayuki
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-09-03
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Epstein-Barr virus (EBV) associated lymphoproliferative disorder (LPD) after immunosuppressive therapy for aplastic anemia (AA) is extremely rare in a nontransplant setting and has not been well described.
This report describes a severe AA patient in whom fatal EBV-LPD developed after being treated with rabbit antithymocyte globulins (ATG) and cyclosporine A (CsA).
An 81-year-old man was diagnosed as having severe AA.
He was started on CsA followed by administration of ATG for five consecutive days.
One month after the start of ATG, persistent fever which was not responsive to antibiotics or antifungal agents developed and atypical lymphocytes emerged in peripheral blood.
Repeated blood cultures were negative.
An extremely high level of EBV virus in his peripheral blood plasma was detected by means of a quantitative real-time PCR assay.
Even after the cessation of CsA, the fever persisted and the peripheral atypical lymphocytes proliferated rapidly.
The patient suffered from respiratory failure, liver dysfunction, and metabolic acidosis.
Rituximab was administered without success and he died.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Takahashi, Tohru& Maruyama, Yumiko& Saitoh, Mayuko& Itoh, Hideto& Yoshimoto, Mitsuru& Tsujisaki, Masayuki. 2015. Fatal Epstein-Barr Virus Reactivation in an Acquired Aplastic Anemia Patient Treated with Rabbit Antithymocyte Globulin and Cyclosporine A. Case Reports in Hematology،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058650
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Takahashi, Tohru…[et al.]. Fatal Epstein-Barr Virus Reactivation in an Acquired Aplastic Anemia Patient Treated with Rabbit Antithymocyte Globulin and Cyclosporine A. Case Reports in Hematology No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1058650
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Takahashi, Tohru& Maruyama, Yumiko& Saitoh, Mayuko& Itoh, Hideto& Yoshimoto, Mitsuru& Tsujisaki, Masayuki. Fatal Epstein-Barr Virus Reactivation in an Acquired Aplastic Anemia Patient Treated with Rabbit Antithymocyte Globulin and Cyclosporine A. Case Reports in Hematology. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058650
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1058650
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر