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Onset of Celiac Disease after Treatment of Chronic Hepatitis C with Interferon Based Triple Therapy
المؤلفون المشاركون
Singh, Amandeep
Zaeri, Nayere
Ho, Immanuel K.
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-11-18
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Background.
Patients treated with interferon (IFN) based therapies may develop exacerbation of autoimmune disease.
We herein present the case of a 53-year-old female patient who developed celiac disease (CD) as a result of triple therapy (interferon, ribavirin, and boceprevir) for chronic HCV.
Case.
53-year-old Caucasian female with past medical history of IV drug abuse was referred for abnormal LFTs.
Laboratory data showed HCV RNA of 4,515,392 IU/mL, HCV genotype 1a, with normal LFTs.
She was treated with 4 weeks of pegylated interferon alfa-2a plus ribavirin, followed by triple therapy using boceprevir for a total of 28 weeks.
Approximately 4 weeks after initiation of triple therapy patient developed loose nonbloody bowel movements and was also found to have anemia.
Biopsies from first and second portions of the duodenum were consistent with CD.
The patient was treated with a gluten-free diet.
Her intestinal symptoms improved and the hemoglobin returned to normal.
Conclusion.
Chronic HCV patients being treated with interferon alfa can develop celiac disease during or after therapy.
For patients with positive autoantibodies, all-oral-IFN-free regimens should be considered.
Celiac disease should be considered in patients who develop CD-like symptoms while on and shortly after cessation of interferon alfa therapy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Singh, Amandeep& Zaeri, Nayere& Ho, Immanuel K.. 2015. Onset of Celiac Disease after Treatment of Chronic Hepatitis C with Interferon Based Triple Therapy. Case Reports in Hepatology،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058665
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Singh, Amandeep…[et al.]. Onset of Celiac Disease after Treatment of Chronic Hepatitis C with Interferon Based Triple Therapy. Case Reports in Hepatology No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1058665
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Singh, Amandeep& Zaeri, Nayere& Ho, Immanuel K.. Onset of Celiac Disease after Treatment of Chronic Hepatitis C with Interferon Based Triple Therapy. Case Reports in Hepatology. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058665
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1058665
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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