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Obstructive Jaundice as Initial Presentation of Multiple Myeloma: Case Presentation and Literature Review
المؤلفون المشاركون
Khan, Yasir
Mansour, Iyad
Ong, Eric
Shrestha, Manish
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-06-21
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Multiple myeloma is a malignant plasma-cell disorder that primarily involves the bone marrow, but extramedullary involvement is becoming increasingly common (Bladé et al., 2012) both at initial presentation and follow-up.
Most common initial presentations for multiple myeloma include generalized fatigue, renal insufficiency, bone pain, and recurrent bacterial infections.
We present a case of a healthy 55-year-old man that presented to the emergency department with a three-week history of anorexia and jaundice without any past medical history.
Patient’s initial labs were significant for hyperbilirubinemia and elevated liver function enzymes (AST, ALT, ALP, and GGT).
Additional laboratory workup was significant for mild hypercalcemia and increased protein gap.
MRI and ERCP suggested primary sclerosing cholangitis but were not diagnostic.
Liver biopsy illustrated plasma-cell infiltration and bone marrow biopsy diagnosed multiple myeloma with extramedullary disease.
Patient was started on dexamethasone, bortezomib, and cyclophosphamide, but, despite this aggressive regimen, the patient continued to decline.
We take this opportunity to present this atypical presentation of a common hematological malignancy and review the associated literature.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Khan, Yasir& Mansour, Iyad& Ong, Eric& Shrestha, Manish. 2015. Obstructive Jaundice as Initial Presentation of Multiple Myeloma: Case Presentation and Literature Review. Case Reports in Medicine،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058888
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Khan, Yasir…[et al.]. Obstructive Jaundice as Initial Presentation of Multiple Myeloma: Case Presentation and Literature Review. Case Reports in Medicine No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1058888
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Khan, Yasir& Mansour, Iyad& Ong, Eric& Shrestha, Manish. Obstructive Jaundice as Initial Presentation of Multiple Myeloma: Case Presentation and Literature Review. Case Reports in Medicine. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058888
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1058888
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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