Clozapine-Induced Late Agranulocytosis and Severe Neutropenia Complicated with Streptococcus pneumonia, Venous Thromboembolism, and Allergic Vasculitis in Treatment-Resistant Female Psychosis
المؤلفون المشاركون
Giannas, Raphael
Kanellou, Anna
Anagnostopoulos, Nikolaos
Pagoni, Stamata
Voulgari, Christina
Paterakis, Georgios
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-02-10
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Clozapine is a second-generation antipsychotic agent from the benzodiazepine group indicated for treatment-resistant schizophrenia and other psychotic conditions.
Using clozapine earlier on once a case appears to be refractory limits both social and personal morbidity of chronic psychosis.
However treatment with second-generation antipsychotics is often complicated by adverse effects.
We present a case of a 33-year-old Caucasian woman with a 25-year history of refractory psychotic mania after switching to a 2-year clozapine therapy.
She presented clozapine-induced absolute neutropenia, agranulocytosis, which were complicated by Streptococcus pneumonia and sepsis.
Clozapine-induced thromboembolism of the common femoral and right proximal iliac vein, as well as allergic vasculitis, was diagnosed.
She achieved full remission on granulocyte-colony stimulating factor and specific antibiotic treatment.
Early detection of severe clozapine-induced absolute neutropenia and agranulocytosis enabled the effective treatment of two among its most severe complications.
Additional evidence to the previously reported possible causal relation between clozapine and venous thromboembolism is offered.
Finally, clozapine-induced allergic vasculitis is confirmed as a late adverse effect of clozapine therapy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Voulgari, Christina& Giannas, Raphael& Paterakis, Georgios& Kanellou, Anna& Anagnostopoulos, Nikolaos& Pagoni, Stamata. 2015. Clozapine-Induced Late Agranulocytosis and Severe Neutropenia Complicated with Streptococcus pneumonia, Venous Thromboembolism, and Allergic Vasculitis in Treatment-Resistant Female Psychosis. Case Reports in Medicine،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1058892
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Voulgari, Christina…[et al.]. Clozapine-Induced Late Agranulocytosis and Severe Neutropenia Complicated with Streptococcus pneumonia, Venous Thromboembolism, and Allergic Vasculitis in Treatment-Resistant Female Psychosis. Case Reports in Medicine No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1058892
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Voulgari, Christina& Giannas, Raphael& Paterakis, Georgios& Kanellou, Anna& Anagnostopoulos, Nikolaos& Pagoni, Stamata. Clozapine-Induced Late Agranulocytosis and Severe Neutropenia Complicated with Streptococcus pneumonia, Venous Thromboembolism, and Allergic Vasculitis in Treatment-Resistant Female Psychosis. Case Reports in Medicine. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1058892
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1058892
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر