Three Siblings with Prader-Willi Syndrome: Brief Review of Sleep and Prader-Willi Syndrome

المؤلفون المشاركون

Bingeliene, Arina
Shapiro, Colin M.
Chung, Sharon A.

المصدر

Case Reports in Neurological Medicine

العدد

المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-5، 5ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2015-11-03

دولة النشر

مصر

عدد الصفحات

5

التخصصات الرئيسية

الطب البشري

الملخص EN

Prader-Willi syndrome (PWS) is a genetic disorder characterized by short stature, mental retardation, hypotonia, functionally deficient gonads, and uncontrolled appetite leading to extreme obesity at an early age.

Patients with this condition require multidisciplinary medical care, which facilitates a significant improvement in quality of life.

PWS is the first human disorder to be attributed to genomic imprinting.

Prevalence varies in the literature, ranging from 1 in 8,000 in the Swedish population to 1 in 54,000 in the United Kingdom.

Rarely, the genetic mechanism responsible for Prader-Willi syndrome can be inherited.

We report a highly unique case of three siblings who share this condition.

This report describes a case of two brothers and one half sister with PWS.

All three siblings have sleep-related complaints.

The sister died at the age of 24 years in her sleep, with the cause of death reported as obstructive sleep apnea.

The outcome was positive in both of the brothers’ cases as a result of professional medical care and specific tailored recommendations implemented by their mother.

A review of the relevant literature vis-à-vis sleep and PWS is provided.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Bingeliene, Arina& Shapiro, Colin M.& Chung, Sharon A.. 2015. Three Siblings with Prader-Willi Syndrome: Brief Review of Sleep and Prader-Willi Syndrome. Case Reports in Neurological Medicine،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1059008

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Bingeliene, Arina…[et al.]. Three Siblings with Prader-Willi Syndrome: Brief Review of Sleep and Prader-Willi Syndrome. Case Reports in Neurological Medicine No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1059008

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Bingeliene, Arina& Shapiro, Colin M.& Chung, Sharon A.. Three Siblings with Prader-Willi Syndrome: Brief Review of Sleep and Prader-Willi Syndrome. Case Reports in Neurological Medicine. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1059008

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1059008