Neuroprotective Effects of Cistanches Herba Therapy on Patients with Moderate Alzheimer’s Disease
المؤلفون المشاركون
Fu, Xiaojie
Wang, Jianping
Li, Nan
Ma, Jun
Gu, Zhiqiang
Jiang, Chao
Yu, Lie
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-09-07
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Cistanches Herba (CH) is thought to be a “Yang-invigorating” material in traditional Chinese medicine.
We evaluated neuroprotective effects of Cistanches Herba on Alzheimer’s disease (AD) patients.
Moderate AD participants were divided into 3 groups: Cistanches Herba capsule (CH, n = 10 ), Donepezil tablet (DON, n = 8 ), and control group without treatment n = 6 .
We assessed efficacy by MMSE and ADAS-cog, and investigated the volume changes of hippocampus by 1.5 T MRI scans.
Protein, mRNA levels, and secretions of total-tau (T-tau), tumor necrosis factor-α (TNF-α), and interleukin- (IL) 1β (IL-1β) in cerebrospinal fluid (CSF) were detected by Western blot, RT-PCR, and ELISA.
The scores showed statistical difference after 48 weeks of treatment compared to control group.
Meanwhile, volume changes of hippocampus were slight in drug treatment groups but distinct in control group; the levels of T-tau, TNF-α, and IL-1β were decreased compared to those in control group.
Cistanches Herba could improve cognitive and independent living ability of moderate AD patients, slow down volume changes of hippocampus, and reduce the levels of T-tau, TNF-α, and IL-1β.
It suggested that Cistanches Herba had potential neuroprotective effects for moderate AD.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Li, Nan& Wang, Jianping& Ma, Jun& Gu, Zhiqiang& Jiang, Chao& Yu, Lie…[et al.]. 2015. Neuroprotective Effects of Cistanches Herba Therapy on Patients with Moderate Alzheimer’s Disease. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1061142
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Li, Nan…[et al.]. Neuroprotective Effects of Cistanches Herba Therapy on Patients with Moderate Alzheimer’s Disease. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1061142
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Li, Nan& Wang, Jianping& Ma, Jun& Gu, Zhiqiang& Jiang, Chao& Yu, Lie…[et al.]. Neuroprotective Effects of Cistanches Herba Therapy on Patients with Moderate Alzheimer’s Disease. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1061142
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1061142
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر