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In Vitro Antistaphylococcal Effects of Embelia schimperi Extracts and Their Component Embelin with Oxacillin and Tetracycline
المؤلفون المشاركون
Patrick, Van Damme
Rondevaldova, Johana
Leuner, Olga
Teka, Alemtshay
Lulekal, Ermias
Havlik, Jaroslav
Kokoska, Ladislav
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-02-23
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Bacterial infections are in less-developed countries traditionally treated by remedies prepared from medicinal plants.
Embelia schimperi (Vatke) is a plant used as a taenicide or disinfectant in Ethiopia, very often taken mixed with another plant species.
In the present study, we examined two extracts prepared from seeds and twigs with leaves of E.
schimperi and its main present secondary metabolite embelin for their antibacterial combinatory effect with oxacillin and tetracycline against sensitive and resistant Staphylococcus aureus strains.
Minimum inhibitory concentrations were determined through the broth microdilution method, whereas the combinatory effect was evaluated through fractional inhibitory concentration sum (ΣFIC) indices.
Results show many positive interactions and synergy occurring in embelin and oxacillin combinations against 4 out of 9 strains (ΣFIC 0.203–0.477) and for embelin and tetracycline combination against 3 out of 9 strains (ΣFIC 0.400–0.496).
Moreover, the resistance to oxacillin has been overcome in 2 strains and to tetracycline in 3 strains.
According to our knowledge, this is the first study showing antimicrobial combinatory effect of E.
schimperi as well as of embelin.
These findings can be used for the further research targeted on the development of new antistaphylococcal agents.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Rondevaldova, Johana& Leuner, Olga& Teka, Alemtshay& Lulekal, Ermias& Havlik, Jaroslav& Patrick, Van Damme…[et al.]. 2015. In Vitro Antistaphylococcal Effects of Embelia schimperi Extracts and Their Component Embelin with Oxacillin and Tetracycline. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1061208
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Rondevaldova, Johana…[et al.]. In Vitro Antistaphylococcal Effects of Embelia schimperi Extracts and Their Component Embelin with Oxacillin and Tetracycline. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1061208
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Rondevaldova, Johana& Leuner, Olga& Teka, Alemtshay& Lulekal, Ermias& Havlik, Jaroslav& Patrick, Van Damme…[et al.]. In Vitro Antistaphylococcal Effects of Embelia schimperi Extracts and Their Component Embelin with Oxacillin and Tetracycline. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1061208
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1061208
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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