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Bathing Effects of Various Seawaters on Allergic (Atopic) Dermatitis-Like Skin Lesions Induced by 2,4-Dinitrochlorobenzene in Hairless Mice
المؤلفون المشاركون
Kim, Choong Gon
Kang, Meehye
Lee, Youn-Ho
Min, Won Gi
Kim, Yong Hwan
Kang, Su Jin
Song, Chang Hyun
Park, Soo Jin
Park, Ji Ha
Han, Chang Hyun
Lee, Young-Joon
Ku, Sae-Kwang
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-25، 25ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-06-16
دولة النشر
مصر
عدد الصفحات
25
التخصصات الرئيسية
الملخص EN
We evaluated the preventive effects of four types of seawater collected in Republic of Korea on hairless mice with 2,4-dinitrochlorobenzene- (DNCB-) induced allergic/atopic dermatitis (AD).
The anti-inflammatory effects were evaluated by measuring tumor necrosis factor- (TNF-) α and interleukins (ILs).
Glutathione (GSH), malondialdehyde (MDA), superoxide anion, and inducible nitric oxide synthase (iNOS) were measured to evaluate the antioxidant effects.
Caspase-3 and poly (ADP-ribose) polymerase (PARP) were observed to measure the antiapoptotic effects; matrix metalloproteinase- (MMP-) 9 levels were also evaluated.
Mice with AD had markedly higher clinical skin severity scores and scratching behaviors; higher TNF-α and ILs (1β, 10, 4, 5, and 13) levels; higher MDA, superoxide anion, caspase-3, PARP, and MMP-9 levels; and greater iNOS activity.
However, the severity of AD was significantly decreased by bathing in seawaters, but it did not influence the dermal collagen depositions and skin tissue antioxidant defense systems.
These results suggest that bathing in all four seawaters has protective effects against DNCB-induced AD through their favorable systemic and local immunomodulatory effects, active cytoprotective antiapoptotic effects, inhibitory effects of MMP activity and anti-inflammatory and antioxidative effects.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kim, Choong Gon& Kang, Meehye& Lee, Youn-Ho& Min, Won Gi& Kim, Yong Hwan& Kang, Su Jin…[et al.]. 2015. Bathing Effects of Various Seawaters on Allergic (Atopic) Dermatitis-Like Skin Lesions Induced by 2,4-Dinitrochlorobenzene in Hairless Mice. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-25.
https://search.emarefa.net/detail/BIM-1061210
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kim, Choong Gon…[et al.]. Bathing Effects of Various Seawaters on Allergic (Atopic) Dermatitis-Like Skin Lesions Induced by 2,4-Dinitrochlorobenzene in Hairless Mice. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-25.
https://search.emarefa.net/detail/BIM-1061210
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kim, Choong Gon& Kang, Meehye& Lee, Youn-Ho& Min, Won Gi& Kim, Yong Hwan& Kang, Su Jin…[et al.]. Bathing Effects of Various Seawaters on Allergic (Atopic) Dermatitis-Like Skin Lesions Induced by 2,4-Dinitrochlorobenzene in Hairless Mice. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-25.
https://search.emarefa.net/detail/BIM-1061210
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1061210
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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