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Active Compounds of Rhubarb Root and Rhizome in Animal Model Experiments of Focal Cerebral Ischemia
المؤلفون المشاركون
Liu, Ai-ju
Song, Liang
Li, Yan
Zhang, Xiao-guang
Chen, Zi-xian
Huang, Li-bo
Zhang, Hong-feng
Zheng, Guo-qing
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-10-01
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Rhubarb root and rhizome (RRR) has been clinically used for stroke at least 2000 years and is still used in modern times in both China and elsewhere worldwide.
The objective of present study was to evaluate the efficacy of active compounds of RRR (ACRRR) for experimental ischemic stroke.
Studies of ACRRR in animal models of ischemic stroke were identified from 5 databases until April 2014.
Study quality for each included article was evaluated according to the CAMARADES 10-item checklist.
Outcome measures were neurological deficit score and infarct size.
All the data were analyzed using RevMan 5.1 software.
As a result, 20 studies were identified describing procedures involving 577 animals.
The quality score of studies ranges from 2 to 6, and the median was 3.4.
Six studies showed significant effects of ACRRR for improving infarct size compared with model group (P<0.01).
Six studies indicated significant effects of ACRRR for improving the neurological deficit scores according to Zea longa criterion or eight-point criterion (P<0.01).
In conclusion, these findings demonstrated a possible efficacy of ACRRR that have potential neuroprotective effect for experimental ischemic stroke.
However, these apparently positive findings should be interpreted with caution because of the methodological flaws.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Liu, Ai-ju& Song, Liang& Li, Yan& Zhang, Xiao-guang& Chen, Zi-xian& Huang, Li-bo…[et al.]. 2015. Active Compounds of Rhubarb Root and Rhizome in Animal Model Experiments of Focal Cerebral Ischemia. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1061246
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Liu, Ai-ju…[et al.]. Active Compounds of Rhubarb Root and Rhizome in Animal Model Experiments of Focal Cerebral Ischemia. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-13.
https://search.emarefa.net/detail/BIM-1061246
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Liu, Ai-ju& Song, Liang& Li, Yan& Zhang, Xiao-guang& Chen, Zi-xian& Huang, Li-bo…[et al.]. Active Compounds of Rhubarb Root and Rhizome in Animal Model Experiments of Focal Cerebral Ischemia. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1061246
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1061246
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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