Efficacy and Safety of Pomegranate Medicinal Products for Cancer
المؤلفون المشاركون
Vlachojannis, Christian
Zimmermann, Benno F.
Chrubasik, Sigrun
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-15، 15ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-03-01
دولة النشر
مصر
عدد الصفحات
15
التخصصات الرئيسية
الملخص EN
Preclinical in vitro and in vivo studies demonstrate potent effects of pomegranate preparations in cancer cell lines and animal models with chemically induced cancers.
We have carried out one systematic review of the effectiveness of pomegranate products in the treatment of cancer and another on their safety.
The PubMed search provided 162 references for pomegranate and cancer and 122 references for pomegranate and safety/toxicity.
We identified 4 clinical studies investigating 3 pomegranate products, of which one was inappropriate because of the low polyphenol content.
The evidence of clinical effectiveness was poor because the quality of the studies was poor.
Although there is no concern over safety with the doses used in the clinical studies, pomegranate preparations may be harmful by inducing synthetic drug metabolism through activation of liver enzymes.
We have analysed various pomegranate products for their content of anthocyanins, punicalagin, and ellagic acid in order to compare them with the benchmark doses from published data.
If the amount of coactive constituents is not declared, patients risk not benefiting from the putative pomegranate effects.
Moreover, pomegranate end products are affected by many determinants.
Their declaration should be incorporated into the regulatory guidance and controlled before pomegranate products enter the market.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Vlachojannis, Christian& Zimmermann, Benno F.& Chrubasik, Sigrun. 2015. Efficacy and Safety of Pomegranate Medicinal Products for Cancer. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-15.
https://search.emarefa.net/detail/BIM-1061282
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Vlachojannis, Christian…[et al.]. Efficacy and Safety of Pomegranate Medicinal Products for Cancer. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-15.
https://search.emarefa.net/detail/BIM-1061282
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Vlachojannis, Christian& Zimmermann, Benno F.& Chrubasik, Sigrun. Efficacy and Safety of Pomegranate Medicinal Products for Cancer. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-15.
https://search.emarefa.net/detail/BIM-1061282
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1061282
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر