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Prophylactic Treatment with Adlay Bran Extract Reduces the Risk of Severe Acute Radiation Dermatitis: A Prospective, Randomized, Double-Blind Study
المؤلفون المشاركون
Kan, Jung-Yu
Hu, Stephen Chu-Sung
Huang, Chih-Jen
Juan, Chiung-Hui
Yuan, Shyng-Shiou F.
Luo, Kuei-Hau
Hou, Ming-Feng
Chuang, Hung-Yi
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-10-01
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Acute radiation dermatitis is a frequent adverse effect in patients with breast cancer undergoing radiotherapy, but there are only a small number of studies providing evidence-based interventions for this clinical condition.
Adlay is a cereal crop that has been previously shown to have anti-inflammatory and antioxidant properties.
In this study, we seek to evaluate the effectiveness of oral prophylactic treatment with adlay bran extract in reducing the risk of severe acute radiation dermatitis.
A total of 110 patients with breast cancer undergoing radiotherapy were analyzed.
Using a prospective, randomized, double-blind design, 73 patients received oral treatment with adlay bran extract and 37 patients received olive oil (placebo).
Treatment was started at the beginning of radiation therapy and continued until the termination of radiation treatment.
Our results showed that the occurrence of severe acute radiation dermatitis (RTOG grade 2 or higher) was significantly lower in patients treated with oral adlay bran extract compared to placebo (45.2% versus 75.7%, adjusted odds ratio 0.24).
No serious adverse effects from adlay bran treatment were noted.
In conclusion, prophylactic oral treatment with adlay bran extract reduces the risk of severe acute radiation dermatitis and may have potential use in patients with breast cancer undergoing radiotherapy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Huang, Chih-Jen& Hou, Ming-Feng& Kan, Jung-Yu& Juan, Chiung-Hui& Yuan, Shyng-Shiou F.& Luo, Kuei-Hau…[et al.]. 2015. Prophylactic Treatment with Adlay Bran Extract Reduces the Risk of Severe Acute Radiation Dermatitis: A Prospective, Randomized, Double-Blind Study. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1061340
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Huang, Chih-Jen…[et al.]. Prophylactic Treatment with Adlay Bran Extract Reduces the Risk of Severe Acute Radiation Dermatitis: A Prospective, Randomized, Double-Blind Study. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1061340
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Huang, Chih-Jen& Hou, Ming-Feng& Kan, Jung-Yu& Juan, Chiung-Hui& Yuan, Shyng-Shiou F.& Luo, Kuei-Hau…[et al.]. Prophylactic Treatment with Adlay Bran Extract Reduces the Risk of Severe Acute Radiation Dermatitis: A Prospective, Randomized, Double-Blind Study. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1061340
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1061340
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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