Antiosteoporosis Activity of New Oriental Medicine Preparation (Kyungokgo Mixed with Water Extract of Hovenia dulcis) on the Ovariectomized Mice
المؤلفون المشاركون
Kim, Jong-Jin
Kang, Kyung-Yun
Yee, Sung-Tae
Hwang, Yun-Ho
Kim, Kwang-Jin
Lee, Sung-Ju
Jeong, Gil-Yeon
Choi, Kyung-Hee
Son, Young-Jin
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-17، 17ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-02-09
دولة النشر
مصر
عدد الصفحات
17
التخصصات الرئيسية
الملخص EN
Protective effect of new oriental medicine (Kyungokgo mixed with water extract of Hovenia dulcis, KOGHD) was assessed on the bone loss induced mice by ovariectomy.
In the in vivo experiments, antiosteoporosis effect of KOGHD was investigated using ovariectomized osteoporosis mice model.
After 6 weeks of treatment, the mice were euthanized, and the effect of Kyungokgo (KOG) and KOGHD on body weight, spleen weigh, thymus weight, uterine weight, serum biochemical indicators, bone weight and length, immune cell population, bone morphometric parameters, and histological stains was observed.
Our results showed that KOGHD prevented the deterioration of trabecular microarchitecture caused by ovariectomy, which were accompanied by the lower levels of bone turnover markers and immune cell population as evidenced by the inhibition of RANKL-mediated osteoclast differentiation without cytotoxic effect on bone marrow derived macrophages (BMMs).
Therefore, these results suggest that the Hovenia dulcis (HD) supplementation in the KOG may also prevent and treat bone loss.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hwang, Yun-Ho& Kim, Kwang-Jin& Kim, Jong-Jin& Kang, Kyung-Yun& Lee, Sung-Ju& Jeong, Gil-Yeon…[et al.]. 2015. Antiosteoporosis Activity of New Oriental Medicine Preparation (Kyungokgo Mixed with Water Extract of Hovenia dulcis) on the Ovariectomized Mice. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-17.
https://search.emarefa.net/detail/BIM-1061422
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hwang, Yun-Ho…[et al.]. Antiosteoporosis Activity of New Oriental Medicine Preparation (Kyungokgo Mixed with Water Extract of Hovenia dulcis) on the Ovariectomized Mice. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-17.
https://search.emarefa.net/detail/BIM-1061422
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hwang, Yun-Ho& Kim, Kwang-Jin& Kim, Jong-Jin& Kang, Kyung-Yun& Lee, Sung-Ju& Jeong, Gil-Yeon…[et al.]. Antiosteoporosis Activity of New Oriental Medicine Preparation (Kyungokgo Mixed with Water Extract of Hovenia dulcis) on the Ovariectomized Mice. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-17.
https://search.emarefa.net/detail/BIM-1061422
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1061422
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر