In Vitro Ion Chelating, Antioxidative Mechanism of Extracts from Fruits and Barks of Tetrapleura tetraptera and Their Protective Effects against Fenton Mediated Toxicity of Metal Ions on Liver Homogenates
المؤلفون المشاركون
Stoller, Marco
Moukette, Bruno Moukette
Pieme, Anatole Constant
Biapa, Prosper Cabral Nya
Njimou, Jacques Romain
Bravi, Marco
Yonkeu Ngogang, Jeanne
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-08-18
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
The aim of the present study was to investigate the antioxidant activity and protective potential of T.
tetraptera extracts against ion toxicity.
The antioxidant activity of the extracts was investigated spectrophotometrically against several radicals (1,1-diphenyl-2-picrylhydrazyl (DPPH•), 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS•), hydroxyl radical (HO•), and nitric oxide (NO•)), followed by the ferric reducing power, total phenols, flavonoid, and flavonol contents.
The effects of the extracts on catalase (CAT), superoxide dismutase (SOD), and peroxidase activities were also determined using the standard methods as well as the polyphenol profile using HPLC.
The results showed that the hydroethanolic extract of T.
tetraptera (CFH) has the lowest IC50 value with the DPPH, ABTS, OH, and NO radicals.
The same extract also exhibited the significantly higher level of total phenols (37.24 ± 2.00 CAE/g dried extract); flavonoids (11.36 ± 1.88 QE/g dried extract); and flavonols contents (3.95 ± 0.39 QE/g dried extract).
The HPLC profile of T.
tetraptera revealed that eugenol (958.81 ± 00 mg/g DW), quercetin (353.78 ± 00 mg/g DW), and rutin (210.54 ± 00 mg/g DW) were higher in the fruit than the bark extracts.
In conclusion, extracts from T.
tetraptera may act as a protector against oxidative mediated ion toxicity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Moukette, Bruno Moukette& Pieme, Anatole Constant& Biapa, Prosper Cabral Nya& Njimou, Jacques Romain& Stoller, Marco& Bravi, Marco…[et al.]. 2015. In Vitro Ion Chelating, Antioxidative Mechanism of Extracts from Fruits and Barks of Tetrapleura tetraptera and Their Protective Effects against Fenton Mediated Toxicity of Metal Ions on Liver Homogenates. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-14.
https://search.emarefa.net/detail/BIM-1061486
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Moukette, Bruno Moukette…[et al.]. In Vitro Ion Chelating, Antioxidative Mechanism of Extracts from Fruits and Barks of Tetrapleura tetraptera and Their Protective Effects against Fenton Mediated Toxicity of Metal Ions on Liver Homogenates. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-14.
https://search.emarefa.net/detail/BIM-1061486
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Moukette, Bruno Moukette& Pieme, Anatole Constant& Biapa, Prosper Cabral Nya& Njimou, Jacques Romain& Stoller, Marco& Bravi, Marco…[et al.]. In Vitro Ion Chelating, Antioxidative Mechanism of Extracts from Fruits and Barks of Tetrapleura tetraptera and Their Protective Effects against Fenton Mediated Toxicity of Metal Ions on Liver Homogenates. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-14.
https://search.emarefa.net/detail/BIM-1061486
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1061486
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر