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Antinociceptive Effects of Spinal Manipulative Therapy on Nociceptive Behavior of Adult Rats during the Formalin Test
المؤلفون المشاركون
Reed, William R.
Onifer, Stephen M.
Sozio, Randall S.
Long, Cynthia R.
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-11-26
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Optimizing pain relief resulting from spinal manipulative therapies, including low velocity variable amplitude spinal manipulation (LVVA-SM), requires determining their mechanisms.
Pain models that incorporate simulated spinal manipulative therapy treatments are needed for these studies.
The antinociceptive effects of a single LVVA-SM treatment on rat nociceptive behavior during the commonly used formalin test were investigated.
Dilute formalin was injected subcutaneously into a plantar hindpaw.
Licking behavior was video-recorded for 5 minutes.
Ten minutes of LVVA-SM at 20° flexion was administered with a custom-made device at the lumbar (L5) vertebra of isoflurane-anesthetized experimental rats ( n = 12 ) beginning 10 minutes after formalin injection.
Hindpaw licking was video-recorded for 60 minutes beginning 5 minutes after LVVA-SM.
Control rats ( n = 12 ) underwent the same methods except for LVVA-SM.
The mean times spent licking the formalin-injected hindpaw of both groups 1–5 minutes after injection were not different.
The mean licking time during the first 20 minutes post-LVVA-SM of experimental rats was significantly less than that of control rats ( P < 0.001 ).
The mean licking times of both groups during the second and third 20 minutes post-LVVA-SM were not different.
Administration of LVVA-SM had a short-term, remote antinociceptive effect similar to clinical findings.
Therefore, mechanistic investigations using this experimental approach are warranted.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Onifer, Stephen M.& Reed, William R.& Sozio, Randall S.& Long, Cynthia R.. 2015. Antinociceptive Effects of Spinal Manipulative Therapy on Nociceptive Behavior of Adult Rats during the Formalin Test. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1062411
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Onifer, Stephen M.…[et al.]. Antinociceptive Effects of Spinal Manipulative Therapy on Nociceptive Behavior of Adult Rats during the Formalin Test. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1062411
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Onifer, Stephen M.& Reed, William R.& Sozio, Randall S.& Long, Cynthia R.. Antinociceptive Effects of Spinal Manipulative Therapy on Nociceptive Behavior of Adult Rats during the Formalin Test. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1062411
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1062411
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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