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Hair Growth Promotion Activity and Its Mechanism of Polygonum multiflorum
المؤلفون المشاركون
Zhao, Ronghua
Yu, Jie
Lin, Pei
He, Yan Ran
Li, Yunfei
Han, Ming-Nuan
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-07-30
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Polygonum multiflorum Radix (PMR) has long history in hair growth promotion and hair coloring in clinical applications.
However, several crucial problems in its clinic usage and mechanisms are still unsolved or lack scientific evidences.
In this research, C57BL/6J mice were used to investigate hair growth promotion activity and possible mechanism of PMR and Polygonum multiflorum Radix Preparata (PMRP).
Hair growth promotion activities were investigated by hair length, hair covered skin ratio, the number of follicles, and hair color.
Regulation effects of several cytokines involved in the hair growth procedure were tested, such as fibroblast growth factor (FGF-7), Sonic Hedgehog (SHH), β-catenin, insulin-like growth factor-1 (IGF-1), and hepatocyte growth factor (HGF).
Oral PMR groups had higher hair covered skin ratio (100 ± 0.00%) than oral PMRP groups (48%~88%).
However, topical usage of PMRP had about 90% hair covered skin ratio.
Both oral administration of PMR and topically given PMRP showed hair growth promotion activities.
PMR was considered to be more suitable for oral administration, while PMRP showed greater effects in external use.
The hair growth promotion effect of oral PMR was most probably mediated by the expression of FGF-7, while topical PMRP promoted hair growth by the stimulation of SHH expression.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Li, Yunfei& Han, Ming-Nuan& Lin, Pei& He, Yan Ran& Yu, Jie& Zhao, Ronghua. 2015. Hair Growth Promotion Activity and Its Mechanism of Polygonum multiflorum. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1062476
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Li, Yunfei…[et al.]. Hair Growth Promotion Activity and Its Mechanism of Polygonum multiflorum. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1062476
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Li, Yunfei& Han, Ming-Nuan& Lin, Pei& He, Yan Ran& Yu, Jie& Zhao, Ronghua. Hair Growth Promotion Activity and Its Mechanism of Polygonum multiflorum. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1062476
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1062476
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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