Effects of Shenque Moxibustion on Behavioral Changes and Brain Oxidative State in Apolipoprotein E-Deficient Mice
المؤلفون المشاركون
Huang, Jian
Liu, Juntian
Cui, Yingxue
Huang, Chang
Han, Li
Huang, Yuhai
Zhao, Baixiao
Lao, Lixing
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-02-22
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Purpose.
To determine whether moxibustion influences the learning and memory behavior of ApoE−/− male mice, and investigate the mechanism of moxibustion on the alteration of oxidized proteins (glial fibrillary acidic protein, β-amyloid) in hippocampus.
Methods.
Thirty-three ApoE−/− mice were randomly divided into 3 groups (n=11/group): moxibustion, sham moxibustion, and no treatment control.
Wild-type C57BL/6 mice n=13 were used for normal control.
Moxibustion was performed with Shenque (RN8) moxibustion for 20 minutes per day, 6 days/week for 12 weeks.
In sham control, the procedure was similar except burning of the moxa stick.
Behavioral tests (step-down test and Morris water maze task) were conducted in the 13th week.
The mice were then sacrificed and the tissues were harvested for immune-histochemical staining.
Results.
In the step-down test, the moxibustion group had shorter reaction time in training record and committed less mistakes compared to sham control.
In immune-histochemical study, the moxibustion group expressed lower level of GFAP and less aggregation of β-amyloid in the hippocampus than the sham control.
Conclusion.
Our findings suggest that moxibustion may enhance learning capability of ApoE−/− mice.
The mechanism may be via inhibiting oxidized proteins (GFAP and β-amyloid) in astrocytes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Liu, Juntian& Zhao, Baixiao& Cui, Yingxue& Huang, Yuhai& Huang, Chang& Huang, Jian…[et al.]. 2015. Effects of Shenque Moxibustion on Behavioral Changes and Brain Oxidative State in Apolipoprotein E-Deficient Mice. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1063614
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Liu, Juntian…[et al.]. Effects of Shenque Moxibustion on Behavioral Changes and Brain Oxidative State in Apolipoprotein E-Deficient Mice. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1063614
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Liu, Juntian& Zhao, Baixiao& Cui, Yingxue& Huang, Yuhai& Huang, Chang& Huang, Jian…[et al.]. Effects of Shenque Moxibustion on Behavioral Changes and Brain Oxidative State in Apolipoprotein E-Deficient Mice. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1063614
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1063614
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر