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Trigonellae Semen Enhances Sperm Motility and the Expression of the Cation Sperm Channel Proteins in Mouse Testes
المؤلفون المشاركون
Park, Seong Kyu
Kim, Hyu Young
Chang, Mun Seog
Kim, Ha Young
Kim, Do Rim
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-10-11
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Genetic defects during spermatogenesis can lead to a reduction in sperm motility and cause male infertility.
The cation channels of sperm (CatSper) play a role in the regulation of hyperactivated sperm motility in mouse testes.
The effect of Trigonellae Semen (TS) on the male reproductive system and CatSper protein in mouse testes during spermatogenesis was examined.
C57BL/c mice were divided into the following five groups: normal, cyclophosphamide- (CP-) only treated (control group), and three groups treated with varying concentrations of TS with CP (100, 500, and 1000 mg/kg TS and 100 mg/kg CP).
Real-time PCR, western blot analysis, and a testosterone immunoassay were performed to assess CatSper protein levels in the five groups.
Additionally, sperm cell counts and motility were examined.
Results indicate that sperm motility and sperm counts increased in the TS treated groups in a dose-dependent manner (p<0.01).
CatSper levels were also significantly higher in the TS treated groups compared to that of the control group (p<0.001).
Therefore, TS treatment could enhance sperm function by promoting spermatogenesis and the expression of CatSper proteins in mouse testes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kim, Do Rim& Kim, Hyu Young& Kim, Ha Young& Chang, Mun Seog& Park, Seong Kyu. 2015. Trigonellae Semen Enhances Sperm Motility and the Expression of the Cation Sperm Channel Proteins in Mouse Testes. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1063628
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kim, Do Rim…[et al.]. Trigonellae Semen Enhances Sperm Motility and the Expression of the Cation Sperm Channel Proteins in Mouse Testes. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1063628
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kim, Do Rim& Kim, Hyu Young& Kim, Ha Young& Chang, Mun Seog& Park, Seong Kyu. Trigonellae Semen Enhances Sperm Motility and the Expression of the Cation Sperm Channel Proteins in Mouse Testes. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1063628
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1063628
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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