Clinical Effect of Shenfu Injection in Patients with Septic Shock: A Meta-Analysis and Systematic Review
المؤلفون المشاركون
Lv, Zheng-Tao
Mou, Zijun
Li, Yi
Wang, Meng
Xu, Qun
Yu, Xuezhong
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-06-14
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Purpose.
To conduct a meta-analysis evaluating the efficacy of Shenfu injection for treating patients with septic shock when compared with conventional therapy.
Methods.
Eight databases including Pubmed, EMBASE, Cochrane Library, ISI Web of Science, CNKI, Wanfang, VIP, and CBM were searched up to October 2014.
Randomized controlled trials assessing the efficacy of Shenfu injection were identified.
Mean arterial pressure, heart rate, lactate, and mortality were included as outcome measurements.
Results.
We analyzed data from 12 randomized controlled trials involving 904 participants.
Compared with conventional therapy, Shenfu injection could further increase the mean arterial pressure at 1 hour (SMD 0.38; 95% CI, 0.01–0.74) and 6 hours (SMD 0.82; 95% CI, 0.03–1.61).
Shenfu injection could further normalize heart rate at 6 hours (SMD −0.90; 95% CI, −1.47–0.33) and clear serum lactate at 6 hours (SMD −0.51; 95% CI, −0.70–0.32) and 24 hours (SMD, 0.52; 95% CI, −0.77–0.26).
As the endpoint of mortality was not unified, it was not meta-analyzed.
Conclusions.
Based on the findings in present review, Shenfu injection is more effective than conventional therapy in increasing mean arterial pressure, normalizing heart rate, clearing serum lactate, and reducing mortality.
These results should be confirmed in higher level clinical trials in the future.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mou, Zijun& Lv, Zheng-Tao& Li, Yi& Wang, Meng& Xu, Qun& Yu, Xuezhong. 2015. Clinical Effect of Shenfu Injection in Patients with Septic Shock: A Meta-Analysis and Systematic Review. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1063695
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mou, Zijun…[et al.]. Clinical Effect of Shenfu Injection in Patients with Septic Shock: A Meta-Analysis and Systematic Review. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1063695
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mou, Zijun& Lv, Zheng-Tao& Li, Yi& Wang, Meng& Xu, Qun& Yu, Xuezhong. Clinical Effect of Shenfu Injection in Patients with Septic Shock: A Meta-Analysis and Systematic Review. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1063695
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1063695
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر