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Effects of Abnormal Savda Munzip on the Proliferation Activity and Migration Ability of Fibroblasts Derived from Hypertrophic Scar In Vitro
المؤلفون المشاركون
Wang, Hujun
Gao, Weicheng
Kong, Menglong
Li, Nan
Shaolin, Ma
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-03-02
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
To explore the effect of ASMq on proliferation and migration ability of the fibroblast derived from HS of donor (HSFbs) in vitro.
Methods.
The HSFbs were cultured from tissue specimens and passaged to the 3~4 generation, which were treated with the different concentrations of ASMq and 5-Fu from 1 to 11 days.
The difference of HSFbs proliferation activity was analyzed by the CCK-8 method.
The HSFbs migration ability in ASMq (0.4 mg/mL) was analyzed by the Cell Scratch method.
Results.
Transmission electron microscope result shows ASMq concentration significantly increases and fibroblast cell structure markedly change in the experimental group.
The proliferation activity of the HSFbs was obviously weakened in ASMq groups than those of the group A ( P < 0.05 ) at seven days.
The group C (0.4 mg/mL) is better suitable than other three ASMq treatment groups.
Cell Migration Assay shows that the migration ability HSFbs was significantly reduced in ASMq (0.4 mg/mL) treatment group compared with those of blank control group at both 24 h and 48 h ( P < 0.05 ).
Conclusions.
These results suggest that ASMq effectively restrains the proliferation and migration ability of the HTSFbs in vitro, which can be one of the mechanisms for the prevention and treatment of HS.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, Hujun& Gao, Weicheng& Kong, Menglong& Li, Nan& Shaolin, Ma. 2015. Effects of Abnormal Savda Munzip on the Proliferation Activity and Migration Ability of Fibroblasts Derived from Hypertrophic Scar In Vitro. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1063706
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, Hujun…[et al.]. Effects of Abnormal Savda Munzip on the Proliferation Activity and Migration Ability of Fibroblasts Derived from Hypertrophic Scar In Vitro. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1063706
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, Hujun& Gao, Weicheng& Kong, Menglong& Li, Nan& Shaolin, Ma. Effects of Abnormal Savda Munzip on the Proliferation Activity and Migration Ability of Fibroblasts Derived from Hypertrophic Scar In Vitro. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1063706
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1063706
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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