Evaluation of a Topical Herbal Agent for the Promotion of Bone Healing

المؤلفون المشاركون

Ko, Chun-Hay
Shum, Wai-Ting
Hung, Leung-Kim
Lam, Ka-Wing
Lau, David Tai-Wai
Leung, Ping-Chung
Ko, Kam Ming
Siu, Wing Sum
Lau, Clara Bik-San
Wat, Elaine

المصدر

Evidence-Based Complementary and Alternative Medicine

العدد

المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-10، 10ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2015-02-25

دولة النشر

مصر

عدد الصفحات

10

التخصصات الرئيسية

الطب البشري

الملخص EN

A topically used Chinese herbal paste, namely, CDNR, was designed to facilitate fracture healing which is usually not addressed in general hospital care.

From our in vitro studies, CDNR significantly inhibited the release of nitric oxide from RAW264.7 cells by 51 to 77%.

This indicated its anti-inflammatory effect.

CDNR also promoted the growth of bone cells by stimulating the proliferation of UMR106 cells up to 18%.

It also increased the biomechanical strength of the healing bone in a drill-hole defect rat model by 16.5% significantly.

This result revealed its in vivo efficacy on facilitation of bone healing.

Furthermore, the detection of the chemical markers of CDNR in the skin and muscle of the treatment area demonstrated its transdermal properties.

However, CDNR did not affect the bone turnover markers in serum of the rats.

With its anti-inflammatory and bone formation properties, CDNR is found effective in promoting bone healing.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Siu, Wing Sum& Ko, Chun-Hay& Lam, Ka-Wing& Wat, Elaine& Shum, Wai-Ting& Lau, Clara Bik-San…[et al.]. 2015. Evaluation of a Topical Herbal Agent for the Promotion of Bone Healing. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1063778

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Siu, Wing Sum…[et al.]. Evaluation of a Topical Herbal Agent for the Promotion of Bone Healing. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1063778

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Siu, Wing Sum& Ko, Chun-Hay& Lam, Ka-Wing& Wat, Elaine& Shum, Wai-Ting& Lau, Clara Bik-San…[et al.]. Evaluation of a Topical Herbal Agent for the Promotion of Bone Healing. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1063778

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1063778