Assessment of Antifungal Activity of Bakuchiol on Oral-Associated Candida spp.
المؤلفون المشاركون
Abdul Razak, Fathilah
Wan Harun, Wan Himratul Aznita
Nordin, Mohd-Al-Faisal
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-11-08
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Bakuchiol is an active component of Psoralea glandulosa and Psoralea corylifolia, used in traditional Chinese medicine.
The study aimed at investigating the antifungal activity of bakuchiol on planktonic and biofilm forms of orally associated Candida species.
The antifungal susceptibility testing was determined by the broth micro dilution technique.
Growth kinetics and cell surface hydrophobicity (CSH) of Candida were measured to assess the inhibitory effect of bakuchiol on Candida planktonic cells.
Biofilm biomass and cellular metabolic activity were quantitatively estimated by the crystal violet (CV) and the 2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-5-[(phenylamino)carbonyl]-2H-tetrazolium hydroxide (XTT) assays.
All Candida strains have been shown to be susceptible to bakuchiol with the MIC ranges from 12.5 to 100 μg/mL.
Significant decrease in specific growth rates and viable counts demonstrates the inhibitory effect of bakuchiol on Candida planktonic cells.
A brief exposure to bakuchiol also reduced CSH of Candida ( P < 0.05 ), indicating altered surface properties of yeast cells towards hydrophobic interfaces.
Biofilm biomass and cell metabolic activity were mostly decreased, except for C.
glabrata ( P = 0.29 ).
The antifungal properties of bakuchiol on Candida species in this in vitro study may give insights into the application in therapeutic strategy against Candida infections.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Nordin, Mohd-Al-Faisal& Abdul Razak, Fathilah& Wan Harun, Wan Himratul Aznita. 2015. Assessment of Antifungal Activity of Bakuchiol on Oral-Associated Candida spp.. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1063798
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Nordin, Mohd-Al-Faisal…[et al.]. Assessment of Antifungal Activity of Bakuchiol on Oral-Associated Candida spp.. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1063798
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Nordin, Mohd-Al-Faisal& Abdul Razak, Fathilah& Wan Harun, Wan Himratul Aznita. Assessment of Antifungal Activity of Bakuchiol on Oral-Associated Candida spp.. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1063798
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1063798
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر