Electroacupuncture Ameliorates the Coronary Occlusion Related Tachycardia and Hypotension in Acute Rat Myocardial Ischemia Model: Potential Role of Hippocampus
المؤلفون المشاركون
Zhou, Meiqi
Wu, Shengbing
Cao, Jian
Zhang, Tianning
Zhou, Yiping
Wang, Keming
Zhu, Guoqi
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-06-29
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Mechanisms for electroacupuncture (EA) in disease treatments are still enigmatic.
Here, we studied whether hippocampus was involved in the protection of EA stimulation on myocardial ischemia injury.
Acute myocardial ischemia (AMI) model was produced.
EA stimulation at heart meridian from Shenmen (HT7) to Tongli (HT5) was applied to rats 3 times a day for continuous three days.
Coronary occlusion related tachycardia and hypotension, indicated by heart rate, mean arterial pressure, and rate pressure product, were apparently impaired after AMI injury.
By contrast, EA stimulating could ameliorate the impairments of heart function (P<0.05).
Interestingly, lesion of CA1 region of hippocampus abolished the protection of EA.
Neuronal activity in CA1 area was affected by AMI.
As evidenced, cell counts, cell types, and frequency of the discharged neurons were facilitated after AMI, while EA stimulation attenuated the abnormalities.
Furthermore, c-Fos expression was significantly facilitated in CA1 area after AMI, which was reduced by EA stimulation.
Correlations were established between c-Fos expression and cell counts of discharged neurons, as well as between heart function and cell counts of discharged neurons.
Taken together, EA stimulation at heart meridian protects against heart dysfunction induced by AMI possibly through suppressing the neuronal activity in CA1 region.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wu, Shengbing& Cao, Jian& Zhang, Tianning& Zhou, Yiping& Wang, Keming& Zhu, Guoqi…[et al.]. 2015. Electroacupuncture Ameliorates the Coronary Occlusion Related Tachycardia and Hypotension in Acute Rat Myocardial Ischemia Model: Potential Role of Hippocampus. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1063808
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wu, Shengbing…[et al.]. Electroacupuncture Ameliorates the Coronary Occlusion Related Tachycardia and Hypotension in Acute Rat Myocardial Ischemia Model: Potential Role of Hippocampus. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1063808
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wu, Shengbing& Cao, Jian& Zhang, Tianning& Zhou, Yiping& Wang, Keming& Zhu, Guoqi…[et al.]. Electroacupuncture Ameliorates the Coronary Occlusion Related Tachycardia and Hypotension in Acute Rat Myocardial Ischemia Model: Potential Role of Hippocampus. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1063808
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1063808
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر