Dezocine Prevents Postoperative Hyperalgesia in Patients Undergoing Open Abdominal Surgery
المؤلفون المشاركون
Yu, Fang
Zhou, Jie
Xia, Suyun
Xu, Huan
Wang, Xiangrui
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-06-11
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Objective.
Postoperative hyperalgesia is very frequent and hard to treat.
Dezocine is widely used and has a modulatory effect for thermal hyperalgesia in animal models.
So, this study was designed to investigate the potential role of dezocine in decreasing postoperative hyperalgesia for patients undergoing open abdominal surgery.
Methods.
This is a randomized, double-blinded, and placebo-controlled trial.
50 patients for elective open gastrectomy were randomly allocated to either a true treatment group (0.15 mg/kg intravenous dezocine at the end of surgery) or a sham treatment group (equivalent volume of saline) in a 1 : 1 ratio.
Patients were followed up for 48 hours postoperatively and pain threshold to Von Frey filaments, pain scores, PCIA consumption, rescue analgesics use, sedation score, and occurrence of postoperative nausea and vomiting were recorded.
Results.
Patients in the true treatment group experienced statistically significantly higher pain threshold on forearm and smaller extent of peri-incisional hyperalgesia than the sham treatment group.
Rescue analgesic use, cumulative PCIA consumption, and pain scores were statistically significantly decreased in the true treatment group compared to the sham treatment group.
Conclusions.
Dezocine offers a significant antihyperalgesic and analgesic effect in patients undergoing elective open gastrectomy for up to 48 hours postoperatively.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yu, Fang& Zhou, Jie& Xia, Suyun& Xu, Huan& Wang, Xiangrui. 2015. Dezocine Prevents Postoperative Hyperalgesia in Patients Undergoing Open Abdominal Surgery. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1063831
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yu, Fang…[et al.]. Dezocine Prevents Postoperative Hyperalgesia in Patients Undergoing Open Abdominal Surgery. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1063831
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yu, Fang& Zhou, Jie& Xia, Suyun& Xu, Huan& Wang, Xiangrui. Dezocine Prevents Postoperative Hyperalgesia in Patients Undergoing Open Abdominal Surgery. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1063831
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1063831
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر