The Adjuvant Activity of Epimedium Polysaccharide-Propolis Flavone Liposome on Enhancing Immune Responses to Inactivated Porcine Circovirus Vaccine in Mice
المؤلفون المشاركون
Fan, Yunpeng
Hou, Weifeng
Guo, Liwei
Guo, Chao
Zhang, Weimin
Ma, Xia
Ma, Lin
Song, Xiaoping
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-11-03
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Objectives.
The adjuvant activity of Epimedium polysaccharide-propolis flavone liposome (EPL) was investigated in vitro and in vivo.
Methods.
In vitro, the effects of EPL at different concentrations on splenic lymphocytes proliferation and mRNA expression of IFN-γ and IL-6 were determined.
In vivo, the adjuvant activities of EPL, EP, and mineral oil were compared in BALB/c mice through vaccination with inactivated porcine circovirus type 2 (PCV2) vaccine.
Results.
In vitro, EPL promoted lymphocytes proliferation and increased the mRNA expression of IFN-γ and IL-6, and the effect was significantly better than EP at all concentrations.
In vivo, EPL significantly promoted the lymphocytes proliferation and the secretion of cytokines and improved the killing activity of NK cells, PCV2-specific antibody titers, and the proportion of T-cell subgroups.
The effects of EPL were significantly better than EP and oil adjuvant at most time points.
Conclusion.
EPL could significantly improve both PCV2-specific cellular and humoral immune responses, and its medium dose had the best efficacy.
Therefore, EPL would be exploited in an effective immune adjuvant for inactivated PCV2 vaccine.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Fan, Yunpeng& Guo, Liwei& Hou, Weifeng& Guo, Chao& Zhang, Weimin& Ma, Xia…[et al.]. 2015. The Adjuvant Activity of Epimedium Polysaccharide-Propolis Flavone Liposome on Enhancing Immune Responses to Inactivated Porcine Circovirus Vaccine in Mice. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1063851
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Fan, Yunpeng…[et al.]. The Adjuvant Activity of Epimedium Polysaccharide-Propolis Flavone Liposome on Enhancing Immune Responses to Inactivated Porcine Circovirus Vaccine in Mice. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1063851
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Fan, Yunpeng& Guo, Liwei& Hou, Weifeng& Guo, Chao& Zhang, Weimin& Ma, Xia…[et al.]. The Adjuvant Activity of Epimedium Polysaccharide-Propolis Flavone Liposome on Enhancing Immune Responses to Inactivated Porcine Circovirus Vaccine in Mice. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1063851
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1063851
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر