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Hepatocellular Carcinoma in Liver Cirrhosis: Surgical Resection versus Transarterial Chemoembolization—A Meta-Analysis
المؤلفون المشاركون
Kapitanov, Teodor
Schmeding, Maximilian
Neumann, Ulf P.
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-01-06
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
We compare the value of TACE to liver resection for patients with BCLC stage A and B HCC.
For patients with HCC in cirrhosis LT is the treatment of choice.
TACE represents the current standard for unresectable BCLC stage B patients not eligible for LT.
Recently liver resection for HCC and significant cirrhosis has become increasingly popular.
A systematic search of the literature and meta-analysis was conducted to identify studies, reporting short- and long-term results of hepatic resection versus TACE for HCC treatment.
The data were analyzed regarding the odds for 30-day mortality and hazard ratio for overall-survival.
12 studies comparing short- and long-term outcome of HR versus TACE for HCC were identified.
Peri-interventional mortality and overall survival were investigated.
Peri-interventional mortality was higher for surgical resection (n.s.), and overall-survival was significantly better for surgically treated patients at one year (P=0.002) and 3 years (P≤0.00001).
The hazard ratio of overall-survival for all twelve studies was 0.70 (P=0.0001) and significantly in favor of surgical treatment.
Although large RCTs are missing and the available data are limited and not homogeneous a reappraisal of the current treatment guidelines should be considered based on the superior long-term outcome for surgically treated patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kapitanov, Teodor& Neumann, Ulf P.& Schmeding, Maximilian. 2015. Hepatocellular Carcinoma in Liver Cirrhosis: Surgical Resection versus Transarterial Chemoembolization—A Meta-Analysis. Gastroenterology Research and Practice،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1064093
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kapitanov, Teodor…[et al.]. Hepatocellular Carcinoma in Liver Cirrhosis: Surgical Resection versus Transarterial Chemoembolization—A Meta-Analysis. Gastroenterology Research and Practice No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1064093
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kapitanov, Teodor& Neumann, Ulf P.& Schmeding, Maximilian. Hepatocellular Carcinoma in Liver Cirrhosis: Surgical Resection versus Transarterial Chemoembolization—A Meta-Analysis. Gastroenterology Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1064093
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1064093
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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