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The Effects of Viral Load Burden on Pregnancy Loss among HIV-Infected Women in the United States
المؤلفون المشاركون
Westreich, Daniel J.
Cates, Jordan E.
Edmonds, Andrew
Wright, Rodney L.
Greenblatt, Ruth M.
Cejtin, Helen E.
Karim, Roksana
Haddad, Lisa B.
Kempf, Mirjam-Colette
Golub, Elizabeth T.
Adimora, Adaora A.
Minkoff, Howard
Colie, Christine
المصدر
Infectious Diseases in Obstetrics and Gynecology
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-10-25
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background.
To evaluate the effects of HIV viral load, measured cross-sectionally and cumulatively, on the risk of miscarriage or stillbirth (pregnancy loss) among HIV-infected women enrolled in the Women’s Interagency HIV Study between 1994 and 2013.
Methods.
We assessed three exposures: most recent viral load measure before the pregnancy ended, log10 copy-years viremia from initiation of antiretroviral therapy (ART) to conception, and log10 copy-years viremia in the two years before conception.
Results.
The risk of pregnancy loss for those with log10 viral load >4.00 before pregnancy ended was 1.59 (95% confidence interval (CI): 0.99, 2.56) times as high as the risk for women whose log10 viral load was ≤1.60.
There was not a meaningful impact of log10 copy-years viremia since ART or log10 copy-years viremia in the two years before conception on pregnancy loss (adjusted risk ratios (aRRs): 0.80 (95% CI: 0.69, 0.92) and 1.00 (95% CI: 0.90, 1.11), resp.).
Conclusions.
Cumulative viral load burden does not appear to be an informative measure for pregnancy loss risk, but the extent of HIV replication during pregnancy, as represented by plasma HIV RNA viral load, predicted loss versus live birth in this ethnically diverse cohort of HIV-infected US women.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cates, Jordan E.& Westreich, Daniel J.& Edmonds, Andrew& Wright, Rodney L.& Minkoff, Howard& Colie, Christine…[et al.]. 2015. The Effects of Viral Load Burden on Pregnancy Loss among HIV-Infected Women in the United States. Infectious Diseases in Obstetrics and Gynecology،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1064376
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cates, Jordan E.…[et al.]. The Effects of Viral Load Burden on Pregnancy Loss among HIV-Infected Women in the United States. Infectious Diseases in Obstetrics and Gynecology No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1064376
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cates, Jordan E.& Westreich, Daniel J.& Edmonds, Andrew& Wright, Rodney L.& Minkoff, Howard& Colie, Christine…[et al.]. The Effects of Viral Load Burden on Pregnancy Loss among HIV-Infected Women in the United States. Infectious Diseases in Obstetrics and Gynecology. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1064376
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1064376
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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