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The Estimation of First-Phase Insulin Secretion by Using Components of the Metabolic Syndrome in a Chinese Population
المؤلفون المشاركون
Hsieh, Chang-Hsun
Pei, Dee
Lin, Jiunn-diann
Hsu, Chun-Hsien
Lian, Wei-Cheng
Wu, Chung-Ze
Chen, Yen-Lin
Liang, Yao-Jen
المصدر
International Journal of Endocrinology
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-03-01
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Aims.
There are two phases of insulin secretion, the first (FPIS) and second phase (SPIS).
In this study, we built equations to predict FPIS with metabolic syndrome (MetS) components and fasting plasma insulin (FPI).
Methods.
Totally, 186 participants were enrolled.
75% of participants were randomly selected as the study group to build equations.
The remaining 25% of participants were selected as the external validation group.
All participants received a frequently sampled intravenous glucose tolerance test, and acute insulin response after the glucose load (AIRg) was obtained.
The AIRg was considered as FPIS.
Results.
When MetS components were only used, the following equation was built: log (FPIS) = 1.477 − 0.119 × fasting plasma glucose (FPG) + 0.079 × body mass index (BMI) − 0.523 × high-density lipoprotein cholesterol (HDL-C).
After FPI was added, the second equation was formulated: log (FPIS) = 1.532 − 0.127 × FPG + 0.059 × BMI - 0.511 × HDL-C + 0.375 × log (FPI), which provided a better accuracy than the first one.
Conclusions.
Using MetS components, the FPIS could be estimated accurately.
After adding FPI into the equation, the predictive power increased further.
We hope that these equations could be widely used in daily practice.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lin, Jiunn-diann& Hsu, Chun-Hsien& Liang, Yao-Jen& Lian, Wei-Cheng& Hsieh, Chang-Hsun& Wu, Chung-Ze…[et al.]. 2015. The Estimation of First-Phase Insulin Secretion by Using Components of the Metabolic Syndrome in a Chinese Population. International Journal of Endocrinology،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1065777
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lin, Jiunn-diann…[et al.]. The Estimation of First-Phase Insulin Secretion by Using Components of the Metabolic Syndrome in a Chinese Population. International Journal of Endocrinology No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1065777
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lin, Jiunn-diann& Hsu, Chun-Hsien& Liang, Yao-Jen& Lian, Wei-Cheng& Hsieh, Chang-Hsun& Wu, Chung-Ze…[et al.]. The Estimation of First-Phase Insulin Secretion by Using Components of the Metabolic Syndrome in a Chinese Population. International Journal of Endocrinology. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1065777
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1065777
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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