Characterization of Olfactory Ensheathing Glial Cells Cultured on PolyurethanePolylactide Electrospun Nonwovens
المؤلفون المشاركون
Grzesiak, Jakub
Fryczkowski, Ryszard
Lis, Anna
Szarek, Dariusz
Laska, Jadwiga
Marycz, Krzysztof
المصدر
International Journal of Polymer Science
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-03-31
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
The aim of this research was to evaluate novel biomaterials for neural regeneration.
The investigated materials were composed of polyurethane (PU) and polylactide (PLDL) blended at three different w/w ratios, that is, 5/5, 6/4, and 8/2 of PU/PLDL.
Ultrathin fibrous scaffolds were prepared using electrospinning.
The scaffolds were investigated for their applicability for nerve regeneration by culturing rat olfactory ensheathing glial cells.
Cells were cultured on the materials for seven days, during which cellular morphology, phenotype, and metabolic activity were analysed.
SEM analysis of the fabricated fibrous scaffolds showed fibers of a diameter mainly lower than 600 μm with unimportant volume of protrusions situated along the fibers, with nonsignificant differences between all analysed materials.
Cells cultured on the materials showed differences in their morphology and metabolic activity, depending on the blend composition.
The most proper morphology, with numerous p75+ and GFAP+ cells present, was observed in the sample 6/4, whereas the highest metabolic activity was measured in the sample 5/5.
However, none of the investigated samples showed cytotoxicity or negatively influenced cellular morphology.
Therefore, the novel electrospun fibrous materials may be considered for regenerative medicine applications, and especially when contacting with highly sensitive nervous cells.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Grzesiak, Jakub& Fryczkowski, Ryszard& Lis, Anna& Szarek, Dariusz& Laska, Jadwiga& Marycz, Krzysztof. 2015. Characterization of Olfactory Ensheathing Glial Cells Cultured on PolyurethanePolylactide Electrospun Nonwovens. International Journal of Polymer Science،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1066861
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Grzesiak, Jakub…[et al.]. Characterization of Olfactory Ensheathing Glial Cells Cultured on PolyurethanePolylactide Electrospun Nonwovens. International Journal of Polymer Science No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1066861
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Grzesiak, Jakub& Fryczkowski, Ryszard& Lis, Anna& Szarek, Dariusz& Laska, Jadwiga& Marycz, Krzysztof. Characterization of Olfactory Ensheathing Glial Cells Cultured on PolyurethanePolylactide Electrospun Nonwovens. International Journal of Polymer Science. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1066861
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1066861
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر