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Sesquiterpene Lactones from Artemisia Genus: Biological Activities and Methods of Analysis
المؤلفون المشاركون
Ivanescu, Bianca
Corciova, Andreia
Miron, Anca
المصدر
Journal of Analytical Methods in Chemistry
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-21، 21ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-10-01
دولة النشر
مصر
عدد الصفحات
21
التخصصات الرئيسية
الملخص EN
Sesquiterpene lactones are a large group of natural compounds, found primarily in plants of Asteraceae family, with over 5000 structures reported to date.
Within this family, genus Artemisia is very well represented, having approximately 500 species characterized by the presence of eudesmanolides and guaianolides, especially highly oxygenated ones, and rarely of germacranolides.
Sesquiterpene lactones exhibit a wide range of biological activities, such as antitumor, anti-inflammatory, analgesic, antiulcer, antibacterial, antifungal, antiviral, antiparasitic, and insect deterrent.
Many of the biological activities are attributed to the α-methylene-γ-lactone group in their molecule which reacts through a Michael-addition with free sulfhydryl or amino groups in proteins and alkylates them.
Due to the fact that most sesquiterpene lactones are thermolabile, less volatile compounds, they present no specific chromophores in the molecule and are sensitive to acidic and basic mediums, and their identification and quantification represent a difficult task for the analyst.
Another problematic aspect is represented by the complexity of vegetal samples, which may contain compounds that can interfere with the analysis.
Therefore, this paper proposes an overview of the methods used for the identification and quantification of sesquiterpene lactones found in Artemisia genus, as well as the optimal conditions for their extraction and separation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ivanescu, Bianca& Miron, Anca& Corciova, Andreia. 2015. Sesquiterpene Lactones from Artemisia Genus: Biological Activities and Methods of Analysis. Journal of Analytical Methods in Chemistry،Vol. 2015, no. 2015, pp.1-21.
https://search.emarefa.net/detail/BIM-1067175
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ivanescu, Bianca…[et al.]. Sesquiterpene Lactones from Artemisia Genus: Biological Activities and Methods of Analysis. Journal of Analytical Methods in Chemistry No. 2015 (2015), pp.1-21.
https://search.emarefa.net/detail/BIM-1067175
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ivanescu, Bianca& Miron, Anca& Corciova, Andreia. Sesquiterpene Lactones from Artemisia Genus: Biological Activities and Methods of Analysis. Journal of Analytical Methods in Chemistry. 2015. Vol. 2015, no. 2015, pp.1-21.
https://search.emarefa.net/detail/BIM-1067175
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1067175
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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