Relationship of Soluble RAGE with Insulin Resistance and Beta Cell Function during Development of Type 2 Diabetes Mellitus
المؤلفون المشاركون
Banu, Laila Anjuman
Biswas, Subrata Kumar
Mohtarin, Sabreena
Mudi, Sonchita Rani
Anwar, Taznuva
Alam, Sheikh Md. Khorshed
Fariduddin, Md.
Arslan, M. Iqbal
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-05-19
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
This study examined whether circulating levels of soluble receptor for advanced glycation end products (sRAGE) alter in prediabetes and correlate with insulin resistance (IR) and beta cell function in prediabetes and newly diagnosed type 2 diabetes mellitus (T2DM).
Subjects without previous history of diabetes were recruited and grouped as control, prediabetes, and newly diagnosed T2DM.
The control subjects (n=40) and people with prediabetes (n=52) and diabetes (n=66) were similar in terms of age, sex, BMI, systolic and diastolic BP, and fasting insulin level.
HOMA-IR was found significantly higher in people with diabetes than control subjects (p<0.001) and people with prediabetes (p=0.005); and HOMA-%B was found significantly deteriorated in people with diabetes (p<0.001) compared to control subjects and people with prediabetes.
However, serum sRAGE levels did not show any significant alteration in people with prediabetes compared to control subjects.
Moreover, univariate and multivariate analyses did not identify any significant correlation and statistical association of sRAGE with HOMA-IR and HOMA-%B in people with prediabetes and newly diagnosed T2DM.
Our data suggest that serum sRAGE levels do not alter in people with prediabetes compared to control subjects and do not correlate or associate with IR and beta cell function during development of T2DM.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Biswas, Subrata Kumar& Mohtarin, Sabreena& Mudi, Sonchita Rani& Anwar, Taznuva& Banu, Laila Anjuman& Alam, Sheikh Md. Khorshed…[et al.]. 2015. Relationship of Soluble RAGE with Insulin Resistance and Beta Cell Function during Development of Type 2 Diabetes Mellitus. Journal of Diabetes Research،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1067833
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Biswas, Subrata Kumar…[et al.]. Relationship of Soluble RAGE with Insulin Resistance and Beta Cell Function during Development of Type 2 Diabetes Mellitus. Journal of Diabetes Research No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1067833
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Biswas, Subrata Kumar& Mohtarin, Sabreena& Mudi, Sonchita Rani& Anwar, Taznuva& Banu, Laila Anjuman& Alam, Sheikh Md. Khorshed…[et al.]. Relationship of Soluble RAGE with Insulin Resistance and Beta Cell Function during Development of Type 2 Diabetes Mellitus. Journal of Diabetes Research. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1067833
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1067833
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر