Cross Talk between Lipid Metabolism and Inflammatory Markers in Patients with Diabetic Retinopathy
المؤلفون المشاركون
Sergentanis, Theodoros N.
Crosby-Nwaobi, Roxanne
Dew, Tracy
Forbes, Angus
Sivaprasad, S.
Chatziralli, Irini P.
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-07-29
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Purpose.
The purpose of this study was to examine the relationship between metabolic and inflammatory markers in patients with diabetic retinopathy (DR).
Methods.
208 adult patients with type 2 diabetes participated in this study and were categorized into (1) mild nonproliferative diabetic retinopathy (NPDR) without clinically significant macular edema (CSME), (2) NPDR with CSME, (3) proliferative diabetic retinopathy (PDR) without CSME, and (4) PDR with CSME.
Variable serum metabolic markers were assessed using immunoassays.
Multinomial logistic regression analysis was performed.
Results.
Diabetes duration and hypertension are the most significant risk factors for DR.
Serum Apo-B and Apo-B/Apo-A ratio were the most significant metabolic risk factors for PDR and CSME.
For every 0.1 g/L increase in Apo-B concentration, the risk of PDR and CSME increased by about 1.20 times.
We also found that 10 pg/mL increase in serum TNF-α was associated with approximately 2-fold risk of PDR/CSME while an increase by 100 pg/mL in serum VEGF concentration correlated with CSME.
Conclusions.
In conclusion, it seems that there is a link between metabolic and inflammatory markers.
Apo-B/Apo-A ratio should be evaluated as a reliable risk factor for PDR and CSME, while the role of increased systemic TNF-α and VEGF should be explored in CSME.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Crosby-Nwaobi, Roxanne& Chatziralli, Irini P.& Sergentanis, Theodoros N.& Dew, Tracy& Forbes, Angus& Sivaprasad, S.. 2015. Cross Talk between Lipid Metabolism and Inflammatory Markers in Patients with Diabetic Retinopathy. Journal of Diabetes Research،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1067852
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Crosby-Nwaobi, Roxanne…[et al.]. Cross Talk between Lipid Metabolism and Inflammatory Markers in Patients with Diabetic Retinopathy. Journal of Diabetes Research No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1067852
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Crosby-Nwaobi, Roxanne& Chatziralli, Irini P.& Sergentanis, Theodoros N.& Dew, Tracy& Forbes, Angus& Sivaprasad, S.. Cross Talk between Lipid Metabolism and Inflammatory Markers in Patients with Diabetic Retinopathy. Journal of Diabetes Research. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1067852
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1067852
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر