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Recognition of Immune Response for the Early Diagnosis and Treatment of Osteoarthritis
المؤلفون المشاركون
Cui, Quanjun
Kandahari, Adrese M.
Yang, Xinlin
Dighe, Abhijit S.
Pan, Dongfeng
المصدر
Journal of Immunology Research
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-05-03
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Osteoarthritis is a common and debilitating joint disease that affects up to 30 million Americans, leading to significant disability, reduction in quality of life, and costing the United States tens of billions of dollars annually.
Classically, osteoarthritis has been characterized as a degenerative, wear-and-tear disease, but recent research has identified it as an immunopathological disease on a spectrum between healthy condition and rheumatoid arthritis.
A systematic literature review demonstrates that the disease pathogenesis is driven by an early innate immune response which progressively catalyzes degenerative changes that ultimately lead to an altered joint microenvironment.
It is feasible to detect this infiltration of cells in the early, and presumably asymptomatic, phase of the disease through noninvasive imaging techniques.
This screening can serve to aid clinicians in potentially identifying high-risk patients, hopefully leading to early effective management, vast improvements in quality of life, and significant reductions in disability, morbidity, and cost related to osteoarthritis.
Although the diagnosis and treatment of osteoarthritis routinely utilize both invasive and non-invasive strategies, imaging techniques specific to inflammatory cells are not commonly employed for these purposes.
This review discusses this paradigm and aims to shift the focus of future osteoarthritis-related research towards early diagnosis of the disease process.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kandahari, Adrese M.& Yang, Xinlin& Dighe, Abhijit S.& Pan, Dongfeng& Cui, Quanjun. 2015. Recognition of Immune Response for the Early Diagnosis and Treatment of Osteoarthritis. Journal of Immunology Research،Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1068397
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kandahari, Adrese M.…[et al.]. Recognition of Immune Response for the Early Diagnosis and Treatment of Osteoarthritis. Journal of Immunology Research No. 2015 (2015), pp.1-13.
https://search.emarefa.net/detail/BIM-1068397
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kandahari, Adrese M.& Yang, Xinlin& Dighe, Abhijit S.& Pan, Dongfeng& Cui, Quanjun. Recognition of Immune Response for the Early Diagnosis and Treatment of Osteoarthritis. Journal of Immunology Research. 2015. Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1068397
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1068397
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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