New Insights about Treg and Th17 Cells in HIV Infection and Disease Progression
المؤلفون المشاركون
Chies, José Artur
Valverde-Villegas, Jacqueline María
Matte, Maria Cristina Cotta
Medeiros, Rúbia Marília de
المصدر
Journal of Immunology Research
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-10-19
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
Treg and Th17 cell subsets are characterized by the expression of specific transcriptional factors and chemokine receptor as well as by secretion of specific cytokine and chemokines.
These subsets are important to the differentiation, expansion, homing capacity, and recruitment of several different immune cell populations to the site of infection.
Whereas Treg cells maintain self-tolerance and control the activation and expansion of autoreactive CD4+ T effector cells through an anti-inflammatory response, Th17 cells, in an exacerbated unregulated proinflammatory response, can promote autoimmunity.
Despite such apparently opposite functions, Th17 and Treg cells share common characteristics, and their differentiation pathways are interconnected.
Recent studies have revealed quite intricate relations between Treg and Th17 cells in HIV infection and progression to AIDS.
Considering Treg cells, different subsets were already investigated in the context of HIV infection, indicating a fluctuation in the total number and frequency throughout the disease course.
This review focuses on the recent findings regarding the role of regulatory T and Th17 cells in the context of HIV infection, highlighting the importance of the balance between these two subsets on disease progression.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Valverde-Villegas, Jacqueline María& Matte, Maria Cristina Cotta& Medeiros, Rúbia Marília de& Chies, José Artur. 2015. New Insights about Treg and Th17 Cells in HIV Infection and Disease Progression. Journal of Immunology Research،Vol. 2015, no. 2015, pp.1-14.
https://search.emarefa.net/detail/BIM-1068542
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Valverde-Villegas, Jacqueline María…[et al.]. New Insights about Treg and Th17 Cells in HIV Infection and Disease Progression. Journal of Immunology Research No. 2015 (2015), pp.1-14.
https://search.emarefa.net/detail/BIM-1068542
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Valverde-Villegas, Jacqueline María& Matte, Maria Cristina Cotta& Medeiros, Rúbia Marília de& Chies, José Artur. New Insights about Treg and Th17 Cells in HIV Infection and Disease Progression. Journal of Immunology Research. 2015. Vol. 2015, no. 2015, pp.1-14.
https://search.emarefa.net/detail/BIM-1068542
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1068542
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر