Evaluation of Anti-TBGL Antibody in the Diagnosis of Tuberculosis Patients in China
المؤلفون المشاركون
Suzuki, Yasuhiko
Zhang, Xiaoyan
Chagan-Yasutan, Haorile
Ashino, Yugo
Hattori, Toshio
Zhao, Jingge
Zhu, Zhaoqin
Chen, Haili
Wan, Yanmin
Xu, Jianqing
المصدر
Journal of Immunology Research
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-08-03
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Tuberculous glycolipid (TBGL) is a component of the Mycobacterium tuberculosis cell wall, and anti-TBGL antibodies are used for serodiagnosis of tuberculosis.
Anti-TBGL IgG and IgA levels were measured in 45 pulmonary TB patients (PTB), 26 extra-pulmonary TB patients (ETB), 16 AIDS-TB patients, and 58 healthy controls (HC) including 39 health care workers (HW) and 19 newly enrolled students (ST).
Anti-TBGL IgG measurements yielded 68.9% and 46.2% sensitivity in PTB and ETB, respectively, and 81.0% specificity.
However, anti-TBGL IgA measurements were significantly less sensitive in detecting ETB than PTB (15.4% versus 46.7% sensitivity) but showed up to 89.7% specificity.
Samples from AIDS-TB patients exhibited low reaction of anti-TBGL IgG and IgA with 6.3% and 12.5% sensitivity, respectively.
Unlike anti-lipoarabinomannan (LAM) IgG that was found to elevate in sputum smearpositive subjects, anti-TBGL IgG and IgA elevated in those with cavitation and bronchiectasis, respectively.
Anti-TBGL IgG in cavitary TB yielded 78.2% sensitivity compared to 57.1% in those otherwise.
Meanwhile, higher anti-TBGL IgA titers were observed in HW than in ST, and increasing anti-TBGL IgG titers were observed in HW on follow-up.
Therefore, higher anti-TBGL antibody titers are present in patients presenting cavities and bronchiectasis and subjects under TB exposure risk.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhao, Jingge& Zhu, Zhaoqin& Zhang, Xiaoyan& Suzuki, Yasuhiko& Chagan-Yasutan, Haorile& Chen, Haili…[et al.]. 2015. Evaluation of Anti-TBGL Antibody in the Diagnosis of Tuberculosis Patients in China. Journal of Immunology Research،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1068610
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhao, Jingge…[et al.]. Evaluation of Anti-TBGL Antibody in the Diagnosis of Tuberculosis Patients in China. Journal of Immunology Research No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1068610
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhao, Jingge& Zhu, Zhaoqin& Zhang, Xiaoyan& Suzuki, Yasuhiko& Chagan-Yasutan, Haorile& Chen, Haili…[et al.]. Evaluation of Anti-TBGL Antibody in the Diagnosis of Tuberculosis Patients in China. Journal of Immunology Research. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1068610
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1068610
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر