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Preparation of Cefquinome Nanoparticles by Using the Supercritical Antisolvent Process
المؤلفون المشاركون
Kefeng, Xiao
Weiqiang, Wang
Dedong, Hu
Zhihui, Hao
Yanpeng, Qu
Yan, Liu
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-11-16
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
The supercritical antisolvent process was used successfully to prepare nanoparticles of cefquinome.
These particles were observed by scanning electron microscope (SEM) and their average diameter was measured by laser particle size analyzer.
In the experiments, dimethyl sulfoxide (DMSO) was selected as solvent to dissolve cefquinome sulfate.
It was confirmed by orthogonal experiments that the concentration of solution was the primary factor in this process followed by feeding speed of solution, precipitation pressure, and precipitation temperature.
Moreover, the optimal conditions of preparing nanoparticles of cefquinome by supercritical antisolvent process were that solution concentration was 100 mg/mL, solution flow speed was 1.5 mL/min, operating pressure was 13 Mpa, and operating temperature was 33°C.
Confirmatory experiment was conducted under this condition.
It was found that the appearance of particles was flakes and the average diameter of particles was 0.71 microns.
Finally, influence law of individual factor on particle size was investigated by univariate analysis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kefeng, Xiao& Weiqiang, Wang & Dedong, Hu& Zhihui, Hao& Yanpeng, Qu& Yan, Liu. 2015. Preparation of Cefquinome Nanoparticles by Using the Supercritical Antisolvent Process. Journal of Nanomaterials،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1069300
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kefeng, Xiao…[et al.]. Preparation of Cefquinome Nanoparticles by Using the Supercritical Antisolvent Process. Journal of Nanomaterials No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1069300
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kefeng, Xiao& Weiqiang, Wang & Dedong, Hu& Zhihui, Hao& Yanpeng, Qu& Yan, Liu. Preparation of Cefquinome Nanoparticles by Using the Supercritical Antisolvent Process. Journal of Nanomaterials. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1069300
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1069300
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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