The Intrauterine and Nursing Period Is a Window of Susceptibility for Development of Obesity and Intestinal Tumorigenesis by a High Fat Diet in Min+ Mice as Adults
المؤلفون المشاركون
Ngo, Ha Thi
Hetland, Ragna Bogen
Steffensen, Inger-Lise
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-25، 25ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-03-19
دولة النشر
مصر
عدد الصفحات
25
التخصصات الرئيسية
الملخص EN
We studied how obesogenic conditions during various life periods affected obesity and intestinal tumorigenesis in adult C57BL/6J-Min (multiple intestinal neoplasia)/+ mice.
The mice were given a 10% fat diet throughout life (negative control) or a 45% fat diet in utero, during nursing, during both in utero and nursing, during adult life, or during their whole life-span, and terminated at 11 weeks for tumorigenesis (Min/+) or 23 weeks for obesogenic effect (wild-type).
Body weight at 11 weeks was increased after a 45% fat diet during nursing, during both in utero and nursing, and throughout life, but had normalized at 23 weeks.
In the glucose tolerance test, the early exposure to a 45% fat diet in utero, during nursing, or during both in utero and nursing, did not affect blood glucose, whereas a 45% fat diet given to adults or throughout life did.
However, a 45% fat diet during nursing or during in utero and nursing increased the number of small intestinal tumors.
So did exposures to a 45% fat diet in adult life or throughout life, but without increasing the tumor numbers further.
The intrauterine and nursing period is a window of susceptibility for dietary fat-induced obesity and intestinal tumor development.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ngo, Ha Thi& Hetland, Ragna Bogen& Steffensen, Inger-Lise. 2015. The Intrauterine and Nursing Period Is a Window of Susceptibility for Development of Obesity and Intestinal Tumorigenesis by a High Fat Diet in Min+ Mice as Adults. Journal of Obesity،Vol. 2015, no. 2015, pp.1-25.
https://search.emarefa.net/detail/BIM-1069620
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ngo, Ha Thi…[et al.]. The Intrauterine and Nursing Period Is a Window of Susceptibility for Development of Obesity and Intestinal Tumorigenesis by a High Fat Diet in Min+ Mice as Adults. Journal of Obesity No. 2015 (2015), pp.1-25.
https://search.emarefa.net/detail/BIM-1069620
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ngo, Ha Thi& Hetland, Ragna Bogen& Steffensen, Inger-Lise. The Intrauterine and Nursing Period Is a Window of Susceptibility for Development of Obesity and Intestinal Tumorigenesis by a High Fat Diet in Min+ Mice as Adults. Journal of Obesity. 2015. Vol. 2015, no. 2015, pp.1-25.
https://search.emarefa.net/detail/BIM-1069620
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1069620
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر