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The Intrauterine and Nursing Period Is a Window of Susceptibility for Development of Obesity and Intestinal Tumorigenesis by a High Fat Diet in Min+ Mice as Adults
المؤلفون المشاركون
Ngo, Ha Thi
Hetland, Ragna Bogen
Steffensen, Inger-Lise
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-25، 25ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-03-19
دولة النشر
مصر
عدد الصفحات
25
التخصصات الرئيسية
الملخص EN
We studied how obesogenic conditions during various life periods affected obesity and intestinal tumorigenesis in adult C57BL/6J-Min (multiple intestinal neoplasia)/+ mice.
The mice were given a 10% fat diet throughout life (negative control) or a 45% fat diet in utero, during nursing, during both in utero and nursing, during adult life, or during their whole life-span, and terminated at 11 weeks for tumorigenesis (Min/+) or 23 weeks for obesogenic effect (wild-type).
Body weight at 11 weeks was increased after a 45% fat diet during nursing, during both in utero and nursing, and throughout life, but had normalized at 23 weeks.
In the glucose tolerance test, the early exposure to a 45% fat diet in utero, during nursing, or during both in utero and nursing, did not affect blood glucose, whereas a 45% fat diet given to adults or throughout life did.
However, a 45% fat diet during nursing or during in utero and nursing increased the number of small intestinal tumors.
So did exposures to a 45% fat diet in adult life or throughout life, but without increasing the tumor numbers further.
The intrauterine and nursing period is a window of susceptibility for dietary fat-induced obesity and intestinal tumor development.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ngo, Ha Thi& Hetland, Ragna Bogen& Steffensen, Inger-Lise. 2015. The Intrauterine and Nursing Period Is a Window of Susceptibility for Development of Obesity and Intestinal Tumorigenesis by a High Fat Diet in Min+ Mice as Adults. Journal of Obesity،Vol. 2015, no. 2015, pp.1-25.
https://search.emarefa.net/detail/BIM-1069620
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ngo, Ha Thi…[et al.]. The Intrauterine and Nursing Period Is a Window of Susceptibility for Development of Obesity and Intestinal Tumorigenesis by a High Fat Diet in Min+ Mice as Adults. Journal of Obesity No. 2015 (2015), pp.1-25.
https://search.emarefa.net/detail/BIM-1069620
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ngo, Ha Thi& Hetland, Ragna Bogen& Steffensen, Inger-Lise. The Intrauterine and Nursing Period Is a Window of Susceptibility for Development of Obesity and Intestinal Tumorigenesis by a High Fat Diet in Min+ Mice as Adults. Journal of Obesity. 2015. Vol. 2015, no. 2015, pp.1-25.
https://search.emarefa.net/detail/BIM-1069620
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1069620
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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