Biodegradable 3D-Porous Collagen Matrix (Ologen)‎ Compared with Mitomycin C for Treatment of Primary Open-Angle Glaucoma: Results at 5 Years

المؤلفون المشاركون

Yuan, Fei
Li, Lei
Chen, Xiuping
Yan, Xiang
Wang, Liyang

المصدر

Journal of Ophthalmology

العدد

المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-7، 7ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2015-05-19

دولة النشر

مصر

عدد الصفحات

7

التخصصات الرئيسية

الطب البشري

الملخص EN

Purpose.

To evaluate the effectiveness and safety of the Ologen as an aid for trabeculectomy performed for primary open-angle glaucoma compared with mitomycin C.

Methods.

In this prospective, randomized, parallel assignment, comparative study, 31 eyes of 21 primary open-angle glaucoma patients were allocated for trabeculectomy with the Ologen implant; another 32 eyes of 23 patients were treated with trabeculectomy augmented with mitomycin C.

The patients were followed up for 5 years and evaluated for intraocular pressure, rate of success, status of the bleb, and adverse events.

Result.

The mean postoperative intraocular pressure was statistically different at 3 m, 6 m, 1 y, 3 y, and 5 y follow-up.

The rates of both complete success P = 0.017 and overall success P = 0.031 in the Ologen group were significantly higher than those in the mitomycin C group.

The difference of the bleb extent and vascularity was statistically significant in both groups.

There was no significant difference in postoperative complication.

Conclusions.

Ologen provides higher rates of surgical success compared with mitomycin C for patients with primary open-angle glaucoma undergoing trabeculectomy.

It may be a new, safe, simple, and effective therapeutic approach for treating primary open-angle glaucoma.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Yuan, Fei& Li, Lei& Chen, Xiuping& Yan, Xiang& Wang, Liyang. 2015. Biodegradable 3D-Porous Collagen Matrix (Ologen) Compared with Mitomycin C for Treatment of Primary Open-Angle Glaucoma: Results at 5 Years. Journal of Ophthalmology،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1069798

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Yuan, Fei…[et al.]. Biodegradable 3D-Porous Collagen Matrix (Ologen) Compared with Mitomycin C for Treatment of Primary Open-Angle Glaucoma: Results at 5 Years. Journal of Ophthalmology No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1069798

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Yuan, Fei& Li, Lei& Chen, Xiuping& Yan, Xiang& Wang, Liyang. Biodegradable 3D-Porous Collagen Matrix (Ologen) Compared with Mitomycin C for Treatment of Primary Open-Angle Glaucoma: Results at 5 Years. Journal of Ophthalmology. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1069798

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1069798