The Effect of Rebamipide on Ocular Surface Disorders Induced by Latanoprost and Timolol in Glaucoma Patients
المؤلفون المشاركون
Munemasa, Yasunari
Tokuda, Naoto
Kitaoka, Yasushi
Matsuzawa, Akiko
Miyamoto, Junsuke
Sakae, Shinsuke
Takagi, Hitoshi
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-05-10
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Purpose.
To examine the efficacy of ophthalmic rebamipide suspensions on ocular surface disorders induced by antiglaucoma eye drops.
Patients and Methods.
Forty eyes of 40 patients receiving latanoprost (0.005%) and timolol (0.5%) were included in this randomized prospective study.
The patients were randomly divided into two groups (n = 20): the rebamipide-treated group and controlgroup.
Changes in intraocular pressure, tear film break-up time (TBUT), and corneal epithelial barrier function were evaluated at baseline, 4 weeks, and 8 weeks after rebamipide administration.
Furthermore, superficial punctate keratopathy severity was evaluated by scoring the lesion area and density.
Results.
There was no significant difference in intraocular pressure before and after rebamipide treatment.
However, corneal epithelial barrier function improved significantly 4 and 8 weeks after rebamipide treatment.
TBUT was partially, but significantly, increased (P = 0.02) 8 weeks after rebamipide treatment, whereas no significant change was observed at 4 weeks.
Additionally, a significant decrease in area and density of keratopathy was observed 8 weeks after rebamipide treatment but not at 4 weeks.
The control group showed no significant difference compared to baseline.
Conclusions.
Our data suggests that rebamipide treatment may reduce the occurrence of drug-induced ocular surface disorder.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tokuda, Naoto& Kitaoka, Yasushi& Matsuzawa, Akiko& Miyamoto, Junsuke& Sakae, Shinsuke& Munemasa, Yasunari…[et al.]. 2015. The Effect of Rebamipide on Ocular Surface Disorders Induced by Latanoprost and Timolol in Glaucoma Patients. Journal of Ophthalmology،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1069811
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tokuda, Naoto…[et al.]. The Effect of Rebamipide on Ocular Surface Disorders Induced by Latanoprost and Timolol in Glaucoma Patients. Journal of Ophthalmology No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1069811
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tokuda, Naoto& Kitaoka, Yasushi& Matsuzawa, Akiko& Miyamoto, Junsuke& Sakae, Shinsuke& Munemasa, Yasunari…[et al.]. The Effect of Rebamipide on Ocular Surface Disorders Induced by Latanoprost and Timolol in Glaucoma Patients. Journal of Ophthalmology. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1069811
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1069811
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر