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Aqueous Levels of Pigment Epithelium-Derived Factor and Macular Choroidal Thickness in High Myopia
المؤلفون المشاركون
Song, Hui
Chen, Wei
Guan, Yubo
He, Guanghui
Xie, Shiyong
Han, Quanhong
Li, Zhiwei
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-09-27
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Purpose.
To investigate the correlation between aqueous and serum levels of pigment epithelium-derived factor (PEDF) and macular choroidal thickness in high myopia patients, both with and without choroidal neovascularization (CNV).
Methods.
Serum and aqueous levels of PEDF were measured by enzyme-linked immunosorbent assay in 36 high myopia patients (36 eyes) with no CNV (non-CNV group), 14 high myopia patients (14 eyes) with CNV (CNV group), and 42 nonmyopia patients (42 eyes) (control group).
Macular choroidal thickness was measured by enhanced-depth imaging optical coherence tomography.
Results.
Aqueous levels of PEDF were significantly higher in CNV group compared with non-CNV (P<0.001) and control (P<0.001) groups.
Macular choroidal thicknesses were significantly decreased in the non-CNV and CNV groups compared with the control (P<0.001) group.
A statistically significant difference (P=0.012) was found between the CNV and non-CNV groups.
There was a positive correlation between aqueous PEDF and macular choroidal thickness in the non-CNV group (P=0.005), but no correlation with the CNV group.
No correlation between serum PEDF and macular choroidal thickness was detected in the three groups.
Conclusion.
Variations in aqueous PEDF levels coincide with changes in macular choroidal thickness in high myopia patients with no CNV, while no such relationship exists in high myopia patients with CNV.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chen, Wei& Guan, Yubo& He, Guanghui& Li, Zhiwei& Song, Hui& Xie, Shiyong…[et al.]. 2015. Aqueous Levels of Pigment Epithelium-Derived Factor and Macular Choroidal Thickness in High Myopia. Journal of Ophthalmology،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1069822
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chen, Wei…[et al.]. Aqueous Levels of Pigment Epithelium-Derived Factor and Macular Choroidal Thickness in High Myopia. Journal of Ophthalmology No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1069822
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chen, Wei& Guan, Yubo& He, Guanghui& Li, Zhiwei& Song, Hui& Xie, Shiyong…[et al.]. Aqueous Levels of Pigment Epithelium-Derived Factor and Macular Choroidal Thickness in High Myopia. Journal of Ophthalmology. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1069822
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1069822
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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