Relationship between Clinical and Immunological Features of Thyroid Autoimmunity and Ophthalmopathy during Pregnancy
المؤلفون المشاركون
Wall, Jack R.
Lahooti, Hooshang
Hibbert, Emily J.
Champion, Bernard
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-12-21
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Problem.
Clinical features of Graves’ hyperthyroidism (GH) generally improve during pregnancy and rebound in the postpartum period.
It is unclear whether the ophthalmopathy that is associated with GH and, less often, Hashimoto’s thyroiditis (HT) changes in parallel with the thyroid associated antibody reactions and clinical features or runs a different course.
Method of Study.
We retrospectively studied 19 patients with autoimmune thyroid disease over 22 pregnancies: 9 pregnancies with GH and 13 with HT.
Ophthalmopathy was defined by NOSPECS class.
Results.
Thyroid peroxidase (TPO) and thyroglobulin (Tg) antibody titres decreased during pregnancy and rose in the postpartum period.
During pregnancy, 5 patients with GH and 4 patients with HT developed mild ophthalmopathy and two patients with GH and HT developed new upper eyelid retraction (UER).
In the postpartum period, eye scores improved in 3 patients with GH and 3 with HT, remained stable in two and 5 patients, respectively, and worsened in 2 patients with GH and one with HT.
Conclusions.
In patients with mild to moderate eye signs associated with GH and HT, the orbital and thyroid reactions ran different courses during pregnancy.
Since no patient had severe ophthalmopathy, we cannot draw definitive conclusions from this preliminary study.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wall, Jack R.& Lahooti, Hooshang& Hibbert, Emily J.& Champion, Bernard. 2015. Relationship between Clinical and Immunological Features of Thyroid Autoimmunity and Ophthalmopathy during Pregnancy. Journal of Thyroid Research،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1070428
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wall, Jack R.…[et al.]. Relationship between Clinical and Immunological Features of Thyroid Autoimmunity and Ophthalmopathy during Pregnancy. Journal of Thyroid Research No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1070428
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wall, Jack R.& Lahooti, Hooshang& Hibbert, Emily J.& Champion, Bernard. Relationship between Clinical and Immunological Features of Thyroid Autoimmunity and Ophthalmopathy during Pregnancy. Journal of Thyroid Research. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1070428
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1070428
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر