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Systemic Inflammatory Markers Are Closely Associated with Atherogenic Lipoprotein Subfractions in Patients Undergoing Coronary Angiography
المؤلفون المشاركون
Guo, Yuan-Lin
Li, Jianjun
Zhang, Yan
Li, Sha
Xu, Rui-Xia
Zhu, Cheng-Gang
Wu, Na-Qiong
Sun, Jing
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-11-25
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Objective.
To investigate the relationship between inflammatory markers and atherogenic lipoprotein subfractions.
Methods.
We studied 520 eligible subjects who were not receiving any lipid-lowering therapy.
The inflammatory markers including white blood cell (WBC) count, high-sensitivity C-reactive protein (hs-CRP), fibrinogen, erythrocyte sedimentation rate (ESR), and D-dimer were measured.
A multimarker inflammatory index was developed.
Low-density lipoprotein (LDL) and high-density lipoprotein (HDL) separation processes were performed using Lipoprint System.
Results.
In age- and sex-adjusted analysis, several inflammatory markers (WBC count, hs-CRP, fibrinogen, and ESR) were positively related to circulating non-HDL cholesterol and remnant cholesterol ( p < 0.05 , all).
Among lipoprotein subfractions, we observed a positive association of inflammatory markers with very low-density lipoprotein cholesterol, small LDL cholesterol, and LDL score ( p < 0.05 , all).
Meanwhile, a negative association was detected between inflammatory markers and mean LDL particle size ( p < 0.05 ) or large HDL cholesterol ( p < 0.05 ).
Moreover, we found that the relationships between multimarker index quartiles and small LDL cholesterol, LDL score, and mean LDL particle size were slightly stronger in patients with CAD.
Conclusions.
Systemic inflammatory markers are positively correlated with small LDL cholesterol and LDL score while being negatively linked with mean LDL particle size and large HDL cholesterol, highlighting the potential contribution to increased cardiovascular risk.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhang, Yan& Li, Sha& Xu, Rui-Xia& Zhu, Cheng-Gang& Guo, Yuan-Lin& Wu, Na-Qiong…[et al.]. 2015. Systemic Inflammatory Markers Are Closely Associated with Atherogenic Lipoprotein Subfractions in Patients Undergoing Coronary Angiography. Mediators of Inflammation،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1072192
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhang, Yan…[et al.]. Systemic Inflammatory Markers Are Closely Associated with Atherogenic Lipoprotein Subfractions in Patients Undergoing Coronary Angiography. Mediators of Inflammation No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1072192
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhang, Yan& Li, Sha& Xu, Rui-Xia& Zhu, Cheng-Gang& Guo, Yuan-Lin& Wu, Na-Qiong…[et al.]. Systemic Inflammatory Markers Are Closely Associated with Atherogenic Lipoprotein Subfractions in Patients Undergoing Coronary Angiography. Mediators of Inflammation. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1072192
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1072192
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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