![](/images/graphics-bg.png)
Inflammatory Bowel Disease: An Overview of Immune Mechanisms and Biological Treatments
المؤلفون المشاركون
Bier, Julia
Paiatto, Lisiery Negrini
Galdino Albuquerque, Cassia
Lopes Souza, Caique
Fernandes, Luis Gustavo Romani
de Mattos, Bruno Rafael Ramos
Garcia, Maellin Pereira Gracindo
Tamashiro, Wirla Maria da Silva Cunha
Simioni, Patricia Ucelli
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-08-03
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Inflammatory bowel diseases (IBD) are characterized by chronic inflammation of the intestinal tract associated with an imbalance of the intestinal microbiota.
Crohn’s disease (CD) and ulcerative colitis (UC) are the most widely known types of IBD and have been the focus of attention due to their increasing incidence.
Recent studies have pointed out genes associated with IBD susceptibility that, together with environment factors, may contribute to the outcome of the disease.
In ulcerative colitis, there are several therapies available, depending on the stage of the disease.
Aminosalicylates, corticosteroids, and cyclosporine are used to treat mild, moderate, and severe disease, respectively.
In Crohn’s disease, drug choices are dependent on both location and behavior of the disease.
Nowadays, advances in treatments for IBD have included biological therapies, based mainly on monoclonal antibodies or fusion proteins, such as anti-TNF drugs.
Notwithstanding the high cost involved, these biological therapies show a high index of remission, enabling a significant reduction in cases of surgery and hospitalization.
Furthermore, migration inhibitors and new cytokine blockers are also a promising alternative for treating patients with IBD.
In this review, an analysis of literature data on biological treatments for IBD is approached, with the main focus on therapies based on emerging recombinant biomolecules.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
de Mattos, Bruno Rafael Ramos& Garcia, Maellin Pereira Gracindo& Bier, Julia& Paiatto, Lisiery Negrini& Galdino Albuquerque, Cassia& Lopes Souza, Caique…[et al.]. 2015. Inflammatory Bowel Disease: An Overview of Immune Mechanisms and Biological Treatments. Mediators of Inflammation،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1072384
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
de Mattos, Bruno Rafael Ramos…[et al.]. Inflammatory Bowel Disease: An Overview of Immune Mechanisms and Biological Treatments. Mediators of Inflammation No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1072384
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
de Mattos, Bruno Rafael Ramos& Garcia, Maellin Pereira Gracindo& Bier, Julia& Paiatto, Lisiery Negrini& Galdino Albuquerque, Cassia& Lopes Souza, Caique…[et al.]. Inflammatory Bowel Disease: An Overview of Immune Mechanisms and Biological Treatments. Mediators of Inflammation. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1072384
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1072384
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)