المؤلفون المشاركون

Mérida, Salvador
Bosch-Morell, Francisco
Navea-Tejerina, Amparo

المصدر

Oxidative Medicine and Cellular Longevity

العدد

المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-12، 12ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2015-04-01

دولة النشر

مصر

عدد الصفحات

12

التخصصات الرئيسية

الأحياء

الملخص EN

Myopia affected approximately 1.6 billion people worldwide in 2000, and it is expected to increase to 2.5 billion by 2020.

Although optical problems can be corrected by optics or surgical procedures, normal myopia and high myopia are still an unsolved medical problem.

They frequently predispose people who have them to suffer from other eye pathologies: retinal detachment, glaucoma, macular hemorrhage, cataracts, and so on being one of the main causes of visual deterioration and blindness.

Genetic and environmental factors have been associated with myopia.

Nevertheless, lack of knowledge in the underlying physiopathological molecular mechanisms has not permitted an adequate diagnosis, prevention, or treatment to be found.

Nowadays several pieces of evidence indicate that oxidative stress may help explain the altered regulatory pathways in myopia and the appearance of associated eye diseases.

On the one hand, oxidative damage associated with hypoxia myopic can alter the neuromodulation that nitric oxide and dopamine have in eye growth.

On the other hand, radical superoxide or peroxynitrite production damage retina, vitreous, lens, and so on contributing to the appearance of retinopathies, retinal detachment, cataracts and so on.

The objective of this review is to suggest that oxidative stress is one of the key pieces that can help solve this complex eye problem.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Bosch-Morell, Francisco& Mérida, Salvador& Navea-Tejerina, Amparo. 2015. Oxidative Stress in Myopia. Oxidative Medicine and Cellular Longevity،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1075756

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Bosch-Morell, Francisco…[et al.]. Oxidative Stress in Myopia. Oxidative Medicine and Cellular Longevity No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1075756

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Bosch-Morell, Francisco& Mérida, Salvador& Navea-Tejerina, Amparo. Oxidative Stress in Myopia. Oxidative Medicine and Cellular Longevity. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1075756

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1075756