Oxidative Stress in Myopia
Joint Authors
Mérida, Salvador
Bosch-Morell, Francisco
Navea-Tejerina, Amparo
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-01
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Myopia affected approximately 1.6 billion people worldwide in 2000, and it is expected to increase to 2.5 billion by 2020.
Although optical problems can be corrected by optics or surgical procedures, normal myopia and high myopia are still an unsolved medical problem.
They frequently predispose people who have them to suffer from other eye pathologies: retinal detachment, glaucoma, macular hemorrhage, cataracts, and so on being one of the main causes of visual deterioration and blindness.
Genetic and environmental factors have been associated with myopia.
Nevertheless, lack of knowledge in the underlying physiopathological molecular mechanisms has not permitted an adequate diagnosis, prevention, or treatment to be found.
Nowadays several pieces of evidence indicate that oxidative stress may help explain the altered regulatory pathways in myopia and the appearance of associated eye diseases.
On the one hand, oxidative damage associated with hypoxia myopic can alter the neuromodulation that nitric oxide and dopamine have in eye growth.
On the other hand, radical superoxide or peroxynitrite production damage retina, vitreous, lens, and so on contributing to the appearance of retinopathies, retinal detachment, cataracts and so on.
The objective of this review is to suggest that oxidative stress is one of the key pieces that can help solve this complex eye problem.
American Psychological Association (APA)
Bosch-Morell, Francisco& Mérida, Salvador& Navea-Tejerina, Amparo. 2015. Oxidative Stress in Myopia. Oxidative Medicine and Cellular Longevity،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1075756
Modern Language Association (MLA)
Bosch-Morell, Francisco…[et al.]. Oxidative Stress in Myopia. Oxidative Medicine and Cellular Longevity No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1075756
American Medical Association (AMA)
Bosch-Morell, Francisco& Mérida, Salvador& Navea-Tejerina, Amparo. Oxidative Stress in Myopia. Oxidative Medicine and Cellular Longevity. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1075756
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1075756