![](/images/graphics-bg.png)
Relationship between Inflammation and Oxidative Stress and Cognitive Decline in the Institutionalized Elderly
المؤلفون المشاركون
Baierle, Marília
Nascimento, Sabrina N.
Moro, Angela M.
Brucker, Natália
Freitas, Fernando
Gauer, Bruna
Durgante, Juliano
Bordignon, Suelen
Zibetti, Murilo
Trentini, Clarissa M.
Grune, Tilman
Breusing, Nicolle
Garcia, Solange C.
Medeiros Frescura Duarte, Marta Maria
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-03-19
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Objective.
Cognitive impairment reduces quality of life and is related to vascular and neurodegenerative disorders.
However, there is also a close relationship between these diseases and oxidative stress.
Thus, the purpose of this study was to assess whether inflammation and oxidative damage are associated with low cognitive performance in the elderly with different housing conditions.
Methods.
The study groups consisted of 32 institutionalized and 25 noninstitutionalized Brazilian elderly subjects.
Oxidative damage, inflammation markers, and cognitive function were evaluated.
Results.
The results demonstrated pronounced oxidative stress in the institutionalized elderly group, which also had a lower antioxidant status compared to noninstitutionalized subjects.
High levels of proinflammatory cytokines were also observed in the institutionalized elderly.
Furthermore, the raised levels of inflammatory markers were correlated with increased oxidative stress, and both were associated with low cognitive performance.
However, based on multiple linear regression analysis, oxidative stress appears to be the main factor responsible for the cognitive decline.
Conclusions.
The findings suggest that individuals with lower antioxidant status are more vulnerable to oxidative stress, which is associated with cognitive function, leading to reduced life quality and expectancy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Baierle, Marília& Nascimento, Sabrina N.& Moro, Angela M.& Brucker, Natália& Freitas, Fernando& Gauer, Bruna…[et al.]. 2015. Relationship between Inflammation and Oxidative Stress and Cognitive Decline in the Institutionalized Elderly. Oxidative Medicine and Cellular Longevity،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1075781
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Baierle, Marília…[et al.]. Relationship between Inflammation and Oxidative Stress and Cognitive Decline in the Institutionalized Elderly. Oxidative Medicine and Cellular Longevity No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1075781
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Baierle, Marília& Nascimento, Sabrina N.& Moro, Angela M.& Brucker, Natália& Freitas, Fernando& Gauer, Bruna…[et al.]. Relationship between Inflammation and Oxidative Stress and Cognitive Decline in the Institutionalized Elderly. Oxidative Medicine and Cellular Longevity. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1075781
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1075781
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)