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Atypical Small Acinar Proliferation: Repeat Biopsy and Detection of High Grade Prostate Cancer
المؤلفون المشاركون
Amin, Ali
Leone, Andrew
Rotker, Katherine
Butler, Christi
Mega, Anthony
Li, Jianhong
Schiff, Stephen F.
Pareek, Gyan
Golijanin, Dragan
Renzulli, Joseph F.
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-09-14
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Purpose.
Atypical small acinar proliferation (ASAP) is diagnosed in 1-2% of prostate biopsies.
30–40% of patients with ASAP may be diagnosed with prostate cancer (PCa) on repeat biopsy.
Our objective was to examine the association between ASAP and subsequent diagnosis of intermediate/high risk PCa.
Materials and Methods.
Ninety-six patients who underwent prostate biopsy from 2000 to 2013 and were diagnosed with ASAP were identified.
Clinicopathologic features were analyzed.
Comparison was made between those with subsequent PCa on repeat biopsy and those with benign repeat pathology.
Results.
56/96 (58%) patients had a repeat biopsy.
22/56 (39%) were subsequently diagnosed with PCa.
There was no significant difference in patients’ characteristics.
Presence of HGPIN on initial biopsy was associated with a benign repeat biopsy (68% versus 23%).
17/22 (77%) had Gleason grade (GG) 3+3 disease and only 5/22 (23%) had GG 3+4 disease.
Conclusions.
22/56 patients (39%) of patients who underwent a subsequent prostate biopsy following a diagnosis of ASAP were found to have PCa.
77% of these men were diagnosed with GG 3+3 PCa.
Only 23% were found to have intermediate risk PCa and no high risk PCa was identified.
Immediate repeat prostate biopsy in patients diagnosed with ASAP may be safely delayed.
A multi-institutional cohort is being analyzed.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Leone, Andrew& Rotker, Katherine& Butler, Christi& Mega, Anthony& Li, Jianhong& Amin, Ali…[et al.]. 2015. Atypical Small Acinar Proliferation: Repeat Biopsy and Detection of High Grade Prostate Cancer. Prostate Cancer،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1075841
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Leone, Andrew…[et al.]. Atypical Small Acinar Proliferation: Repeat Biopsy and Detection of High Grade Prostate Cancer. Prostate Cancer No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1075841
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Leone, Andrew& Rotker, Katherine& Butler, Christi& Mega, Anthony& Li, Jianhong& Amin, Ali…[et al.]. Atypical Small Acinar Proliferation: Repeat Biopsy and Detection of High Grade Prostate Cancer. Prostate Cancer. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1075841
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1075841
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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