Altered Brain Activation in Early Drug-Naive Parkinson’s Disease during Heat Pain Stimuli: An fMRI Study
المؤلفون المشاركون
Yao, Dezhong
Luo, Cheng
Tan, Ying
Tan, Juan
Cui, Wenjuan
He, Hui
Bin, Yi
Deng, Jiayan
Tan, Rui
Tan, Wenrong
Liu, Tao
Zeng, Nanlin
Xiao, Ruhui
Wang, Xiaoming
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-01-05
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Parkinson’s disease (PD) is a progressive neurodegenerative disease characterized by motor and nonmotor signs and symptoms.
To date, many studies of PD have focused on its cardinal motor symptoms.
To study the nonmotor signs of early PD, we investigated the reactions solicited by heat pain stimuli in early untreated PD patients without pain using fMRI.
The activation patterns of contact heat stimuli (51°C) were assessed in 14 patients and 17 age- and sex-matched healthy controls.
Patients with PD showed significant decreases in activation of the superior temporal gyrus (STG) and insula compared with controls.
In addition, a significant relationship between activation of the insula and STG and the pain scores was observed in healthy controls but not in PD.
This study provided further support that the insula and STG are important parts of the somatosensory circuitry recruited during the period of pain.
The hypoactivity of the STG and insula in PD implied that functions including affective, cognitive, and sensory-discriminative processes, which are associated with the insula and STG, were disturbed.
This finding supports the view that leaving early PD untreated could be tied directly to central nervous system dysfunction.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tan, Ying& Tan, Juan& Luo, Cheng& Cui, Wenjuan& He, Hui& Bin, Yi…[et al.]. 2015. Altered Brain Activation in Early Drug-Naive Parkinson’s Disease during Heat Pain Stimuli: An fMRI Study. Parkinson’s Disease،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1075860
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tan, Ying…[et al.]. Altered Brain Activation in Early Drug-Naive Parkinson’s Disease during Heat Pain Stimuli: An fMRI Study. Parkinson’s Disease No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1075860
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tan, Ying& Tan, Juan& Luo, Cheng& Cui, Wenjuan& He, Hui& Bin, Yi…[et al.]. Altered Brain Activation in Early Drug-Naive Parkinson’s Disease during Heat Pain Stimuli: An fMRI Study. Parkinson’s Disease. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1075860
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1075860
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر