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To Investigate the Effect of Colchicine in Prevention of Adhesions Caused by Serosal Damage in Rats
المؤلفون المشاركون
Koca, Yavuz Savas
Yıldız, İhsan
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-09-28
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Introduction and Aim.
Adhesion formation is a process which starts with an inflammation caused by a number of factors and eventually results in fibrosis.
Colchicine prevents adhesion formation which is antifibrous process.
The effectivity of colchicine in the prevention of adhesions was investigated.
Materials and Methods.
A total of 36 rats were equally divided into three groups: (I) control group 1 ( n = 12 ), (II) abrasion group 2 ( n = 12 ), and (III) abrasion + colchicine group 3 ( n = 12 ).
Group 1 underwent laparotomy and was orally given physiological serum 2 cc/day for 10 days.
In Group 2, injury was created in the cecum serosa following laparotomy and they were orally given physiological serum 2 cc/day for 10 days.
In Group 3, injury was created in the cecum serosa following laparotomy and the rats were orally given colchicine 50 mcg kg/day mixed with physiological serum 2 cc/day for 10 days.
Laparotomy was performed and adhesions were examined both macroscopically and microscopically.
Both macroscopic and microscopic examinations were performed using Zühlke’s score.
Results.
A significant difference was observed among the adhesion scores of the groups both macroscopically and microscopically.
Macroscopic score was lower in group 3 than group 2.
Microscopic score was lower in group 3 than group 2.
Conclusion.
Oral administration of colchicine is effective in the prevention of adhesions.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yıldız, İhsan& Koca, Yavuz Savas. 2015. To Investigate the Effect of Colchicine in Prevention of Adhesions Caused by Serosal Damage in Rats. Surgery Research and Practice،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1076579
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yıldız, İhsan& Koca, Yavuz Savas. To Investigate the Effect of Colchicine in Prevention of Adhesions Caused by Serosal Damage in Rats. Surgery Research and Practice No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1076579
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yıldız, İhsan& Koca, Yavuz Savas. To Investigate the Effect of Colchicine in Prevention of Adhesions Caused by Serosal Damage in Rats. Surgery Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1076579
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1076579
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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