Performance of LED Fluorescence Microscopy for the Diagnosis of Pulmonary Tuberculosis in HIV Positive Individuals in Addis Ababa, Ethiopia
المؤلفون المشاركون
Getachew, Konjit
Abebe, Tamrat
Kebede, Abebaw
Melkamu, Getachew
Mihret, Adane
المصدر
Tuberculosis Research and Treatment
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-11-24
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Despite its lower sensitivity, smear microscopy remains the main diagnostic method for pulmonary tuberculosis (PTB) in resource-limited countries as TB culturing methods like LJ (Lowenstein-Jensen) are expensive to use as a routine base.
This study aimed to evaluate the performance of LED-FM for the diagnosis of PTB in HIV positive individuals.
Methods.
Cross-sectional study was conducted in Zewditu Memorial Hospital and Teklehaimanot Health Center HIV/ART clinics in Addis Ababa, Ethiopia.
Each sample was stained with ZN and Auramine O staining and examined with bright-field microscope and LED-FM microscope, respectively.
LJ culture was used as a reference.
Results.
Out of 178 study participants, twenty-four (13.5%) patients were confirmed as positive for MTB with LJ culture.
The yield of ZN microscopy and LED-FM in direct and concentrated sample was 3.9%, 8.4%, 6.2%, and 8.4%, respectively.
Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of direct ZN microscopy were 29.2%, 100%, 100%, and 90.1%, respectively, and of LED-FM microscopy in direct sputum sample were 62.5%, 100%, 100%, and 94.5%, respectively.
Conclusion.
LED-FM has better sensitivity for the diagnosis of PTB in HIV positive individuals as compared to conventional ZN microscopy.
LED-FM can be used as an alternative to conventional ZN microscopy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Getachew, Konjit & Abebe, Tamrat& Kebede, Abebaw& Mihret, Adane& Melkamu, Getachew. 2015. Performance of LED Fluorescence Microscopy for the Diagnosis of Pulmonary Tuberculosis in HIV Positive Individuals in Addis Ababa, Ethiopia. Tuberculosis Research and Treatment،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1078441
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Getachew, Konjit…[et al.]. Performance of LED Fluorescence Microscopy for the Diagnosis of Pulmonary Tuberculosis in HIV Positive Individuals in Addis Ababa, Ethiopia. Tuberculosis Research and Treatment No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1078441
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Getachew, Konjit & Abebe, Tamrat& Kebede, Abebaw& Mihret, Adane& Melkamu, Getachew. Performance of LED Fluorescence Microscopy for the Diagnosis of Pulmonary Tuberculosis in HIV Positive Individuals in Addis Ababa, Ethiopia. Tuberculosis Research and Treatment. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1078441
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1078441
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر